ID A0A096N0B2_PAPAN Unreviewed; 229 AA.
AC A0A096N0B2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Enhancer of zeste 2 polycomb repressive complex 2 subunit {ECO:0000313|Ensembl:ENSPANP00000005684.3};
GN Name=EZH2 {ECO:0000313|Ensembl:ENSPANP00000005684.3};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000005684.3, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000005684.3, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000005684.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A096N0B2; -.
DR STRING; 9555.ENSPANP00000005684; -.
DR Ensembl; ENSPANT00000021668.3; ENSPANP00000005684.3; ENSPANG00000018691.3.
DR eggNOG; KOG1079; Eukaryota.
DR GeneTree; ENSGT00940000155013; -.
DR HOGENOM; CLU_011342_0_0_1; -.
DR OrthoDB; 902834at2759; -.
DR Proteomes; UP000028761; Chromosome 4.
DR Bgee; ENSPANG00000018691; Expressed in thymus and 64 other cell types or tissues.
DR ExpressionAtlas; A0A096N0B2; baseline.
DR GO; GO:0140951; F:histone H3K27 trimethyltransferase activity; IEA:UniProtKB-EC.
DR InterPro; IPR021654; EZH1/EZH2.
DR Pfam; PF11616; EZH2_WD-Binding; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028761}.
FT REGION 15..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 229 AA; 25532 MW; B7A14CCE5A5D9F56 CRC64;
MAIGLPRLAL GPVASDTRWD TEGSGAPAAA AARGGDAREQ REPARGTKVT RRCGRPGRWG
SRSAKQATAA AAEPPRRCCA GPGIIMGQTG KKSEKGPVCW RKRVKSEYMR LRQLKRFRRA
DEVKSMFSSN RQKILERTEI LNQEWKQRRI QPVHILTSVS SLRGTREAIH LLFPLRFSIT
QFLLGTSLLP RVSVWLCTPT TTIFGLTSLS SSQWSSHTVA YCTSWLIVR
//
