ID A0A096N0N7_PAPAN Unreviewed; 1266 AA.
AC A0A096N0N7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=TBC1 domain family member 9 {ECO:0000313|Ensembl:ENSPANP00000005825.2};
GN Name=TBC1D9 {ECO:0000313|Ensembl:ENSPANP00000005825.2};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000005825.2, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000005825.2, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000005825.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A096N0N7; -.
DR STRING; 9555.ENSPANP00000005825; -.
DR Ensembl; ENSPANT00000013987.3; ENSPANP00000005825.2; ENSPANG00000016781.3.
DR eggNOG; KOG4347; Eukaryota.
DR GeneTree; ENSGT00940000157878; -.
DR HOGENOM; CLU_003535_0_1_1; -.
DR OrthoDB; 3034081at2759; -.
DR Proteomes; UP000028761; Chromosome 3.
DR Bgee; ENSPANG00000016781; Expressed in cerebellum and 66 other cell types or tissues.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd13351; PH-GRAM1_TCB1D9_TCB1D9B; 1.
DR CDD; cd13354; PH-GRAM2_TCB1D9_TCB1D9B; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR036014; TCB1D9/TCB1D9B_PH-GRAM1.
DR InterPro; IPR036017; TCB1D9/TCB1D9B_PH-GRAM2.
DR PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47666:SF2; TBC1 DOMAIN FAMILY MEMBER 9; 1.
DR Pfam; PF02893; GRAM; 2.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00568; GRAM; 2.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761}.
FT DOMAIN 515..702
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT DOMAIN 886..921
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 415..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1075..1095
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1117..1164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1139
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1266 AA; 143257 MW; FBAF6F86927E21E1 CRC64;
MWVNPEEVLL ANALWITERA NPYFILQRRK GHAGDGGGGG GLAGLLVGTL DVVLDSSARV
APYRILYQTP DSLVYWTIAC GGSRKEITEH WEWLEQNLLQ TLSIFENEND ITTFVRGKIQ
GIIAEYNKIN DVKEDDDTEK FKEAIVKFHR LFGMPEEEKL VNYYSCSYWK GKVPRQGWMY
LSINHLCFYS FLMGREAKLV IRWVDITQLE KNATLLLPDV IKVSTRSSEH FFSVFLNINE
TFKLMEQLAN IAMRQLLDNE GFEQDRSLPK LKRKSPKKVS ALKRDLDARA KSERYRALFR
LPKDEKLDGH TDCTLWTPFN KMHILGQMFV STNYICFTSK EENLCSLIIP LREVTIVEKA
DSSSVLPSPL SISTRNRMTF LFANLKDRDF LVQRISDFLQ QTTSKIYSDK EFAGSYNSSD
DEVYSRPSSL VSSSPQRSTS SDADGERQFN LNGNSVPTAT QTLMTMYRRR SPEEFNPKLA
KEFLKEQAWK IHFAEYGQGI CMYRTEKTRE LVLKGIPESM RGELWLLLSG AINEKATHPG
YYEDLVEKSM GKYNLATEEI ERDLHRSLPE HPAFQNEMGI AALRRVLTAY AFRNPNIGYC
QAMNIVTSVL LLYAKEEEAF WLLVALCERM LPDYYNTRVV GALVDQGVFE ELARDYVPQL
YDCMQDLGVI STISLSWFLT LFLSVMPFES AVVVVDCFFY EGIKVIFQLA LAVLDANVDK
LLNCKDDGEA MTVLGRYLDS VTNKDSTLPP IPHLHSLLSD DVEPYPEVDI FRLIRTSYEK
FGTIRADLIE QMRFKQRLKV IQTLEDTTKR NVVRTIVTET SFTIDELEEL YALFKAEHLT
SCYWGGSSNA LDRHDPSLPY LEQYRIDFEQ FKGMFALLFP WACGTHSDVL ASRLFQLLDE
NGDSLINFRE FVSGLSAACH GDLTEKLKLL YKMHVLPEPS SDQDEPDSAF EATQYFFEDI
TPECTHVVGL DSRSKQGADD GFVTVSLKPD KGKRANSQEN RNYLRLWTPE NKSKSKNAKD
LPKLNQGQFI ELCKTMYNMF SEDPNEQELY HATAAVTSLL LEIGEVGKLF VAQPAKEGGS
GGSGPSCHQG IPGVLFPKKG PGQPYVVESV EPLPVSLAPD SEEHSLGGQM EDIKLEDSSP
RDNGACSSML ISDDDTKDDS SMSSYSVLSA GSHEEDKLHC EDIGEDTVLV RSGQGTAALP
RSTSLDRDWA ITFEQFLASL LTEPALVKYF DKPVCMMARI TSAKNIRMMG KPLTSASDYE
ISAMSG
//
