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Database: UniProt
Entry: A0A096NHJ8_PAPAN
LinkDB: A0A096NHJ8_PAPAN
Original site: A0A096NHJ8_PAPAN 
ID   A0A096NHJ8_PAPAN        Unreviewed;      2676 AA.
AC   A0A096NHJ8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 2.
DT   28-MAR-2018, entry version 30.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor type 3 {ECO:0000313|Ensembl:ENSPANP00000012446};
GN   Name=ITPR3 {ECO:0000313|Ensembl:ENSPANP00000012446};
OS   Papio anubis (Olive baboon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Papio.
OX   NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000012446, ECO:0000313|Proteomes:UP000028761};
RN   [1] {ECO:0000313|Ensembl:ENSPANP00000012446, ECO:0000313|Proteomes:UP000028761}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A.,
RA   Aqrawi P.A., Arias F.A., Attaway T.A., Awwad R.A., Babu C.B.,
RA   Bandaranaike D.B., Battles P.B., Bell A.B., Beltran B.B.,
RA   Berhane-Mersha D.B., Bess C.B., Bickham C.B., Bolden T.B.,
RA   Carter K.C., Chau D.C., Chavez A.C., Clerc-Blankenburg K.C.,
RA   Coyle M.C., Dao M.D., Davila M.L.D., Davy-Carroll L.D., Denson S.D.,
RA   Dinh H.D., Fernandez S.F., Fernando P.F., Forbes L.F., Francis C.F.,
RA   Francisco L.F., Fu Q.F., Garcia-Iii R.G., Garrett T.G., Gross S.G.,
RA   Gubbala S.G., Hirani K.H., Hogues M.H., Hollins B.H., Jackson L.J.,
RA   Javaid M.J., Jhangiani S.J., Johnson A.J., Johnson B.J., Jones J.J.,
RA   Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K., Kovar C.K.,
RA   Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA   Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA   Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA   Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA   Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA   Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P.,
RA   Perez Y.P., Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q.,
RA   Rouhana J.R., Ruiz M.R., Ruiz S.-J.R., Saada N.S., Santibanez J.S.,
RA   Scheel M.S., Schneider B.S., Simmons D.S., Sisson I.S., Tang L.-Y.T.,
RA   Thornton R.T., Tisius J.T., Toledanes G.T., Trejos Z.T., Usmani K.U.,
RA   Varghese R.V., Vattathil S.V., Vee V.V., Walker D.W.,
RA   Weissenberger G.W., White C.W., Williams A.W., Woodworth J.W.,
RA   Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N., Nazareth L.N.,
RA   Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT   "Whole Genome Assembly of Papio anubis.";
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPANP00000012446}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AHZZ02024528; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHZZ02024529; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPANT00000026212; ENSPANP00000012446; ENSPANG00000017411.
DR   GeneTree; ENSGT00760000119152; -.
DR   OMA; VVVFYND; -.
DR   OrthoDB; EOG091G00T2; -.
DR   Proteomes; UP000028761; Chromosome 4.
DR   ExpressionAtlas; A0A096NHJ8; baseline.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028761};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2206   2231       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2243   2261       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2273   2293       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2329   2354       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2374   2396       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2503   2526       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      113    173       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      174    224       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      232    288       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      300    377       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      383    439       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED       90    110       {ECO:0000256|SAM:Coils}.
FT   COILED     2634   2661       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2676 AA;  304633 MW;  5AD53D45E4C58F3B CRC64;
     MSEMSSFLHI GDIVSLYAEG SVNGFISTLG LVDDRCVVEP AAGDLDNPPK KFRDCLFKVC
     PMNRYSAQKQ YWKAKQTKQD KEKIADVVLL QKLQHAAQME QKQNDTENKK VHGDVVKYGS
     VIQLLHMKSN KYLTVNKRLP ALLEKNAMRV TLDATGNEGS WLFIQPFWKL RSNGDNVVVG
     DKVILNPVNA GQPLHASNYE LSDNAGCKEV NSVNCNTSWK INLFMQFRDH LEEVLKGGDV
     VRLFHAEQEK FLTCDEYKGK LQVFLRTTLR QSATSATSSN ALWEVEVRRA LWSTTTPCRG
     GAGHWNGLYR FKHLATGNYL AAEENPSYKG DALDPKATGM GAQGRAGRRN AGEKIKYRLV
     AVPHGNDIAS LFELDPTTLQ KTDSFVPRNS YVRLRHLCTN TWIQSTNVPI DIEEERPIRL
     MLGTCPTKED KEAFAIVSVP VSEIRDLDFA NDASSMLASA VEKLNEGFIS QNDRRFVIQL
     LEDLVFFVSD VPNNGQNVLD IMVTKPNRER QKLMREQNIL KQIFGILKAP FREKGGEGPL
     VRLEELSDQK NAPYQHMFRL CYRVLRHSQE DYRKNQEHIA KQFGMMQSQI GYDILAEDTI
     TALLHNNRKL LEKHITKTEV ETFVSLVRKN REPRFLDYLS DLCVSNHIAI PVTQELICKC
     VLDPKNSDIL IQTELRPVKE MAQSHEYLSI EYSDEEVWLT WTDKNNEHHE KSVRQLAQEA
     RAGNAHDENV LSYYRYQLKL FARMCLDRQY LAIDEISQQL GVDLIFLCMA DEMLPFDLRA
     SFCHLMLHVH VDRDPQELVT PVKFARLWTE IPTAITIKDY DSNLNASRDD KKNKFANTME
     FVEDYLNNVV SEAVPFANEE KNKLTFEVVS LAHNLIYFGF YSFSELLRLT RTLLGIIDCV
     QGPPAMLQAY EDPGGKNVRR SIQGVGHMMS TMVLSRKQSV FGAPSLPAGA SAAEPLDRSK
     FEENEDIVVM ETKLKILEIL QFILNVRLDY RISYLLSVFK KEFVEVFPMQ DSGADGTAPA
     FDSTTANMNL DRIGEQAEAM FGVGKTSSML EVDDEGGRMF LRVLIHLTMH DYAPLVSGAL
     QLLFKHFSQR QEAMHTFKQV QLLISAQDVE NYKVIKSELD RLRTMVEKSE LWVDKKGSGK
     GEEVEAGAAK DKKERPTDEE GFLHPPGEKS SENYQIVKGI LERLNKMCGV GEQMRKKQQR
     LLKNMDAHKV MLDLLQIPYD KGDAKMMEIL RYTHQFLQKF CAGNPGNQAL LHKHLHLFLT
     PGLLEAETMQ HIFLNNYQLC SEISEPVLQH FVHLLATHGR HVQYLDFLHT VIKAEGKYVK
     KCQDMIMTEL TNAGDDVVVF YNDKASLAHL LDMMKAARDG VEDHSPLMYH ISLVDLLAAC
     AEGKNVYTEI KCTSLLPLED VVSVVTHEDC ITEVKMAYVN FVNHCYVDTE VEMKEIYTSN
     HIWTLFENFT LDMARVCSKR EKRVADPALE KYVLSVVLDT INAFFSSPFS ENSTSLQTHQ
     TIVVQLLQST TRLLECPWLQ QQHKGSVEAC IRTLAMVAKG RAISLPMDLD AHISAMLSSG
     ASCAAAAQRN ASSYKATTRA FPRVTPTANQ WDYKNIIEKL QDIITALEER LKPLVQAELS
     VLVDVLHWPE LLFLEGSEAY QRCESGGFLS KLIQHTKDLM ESEEKLCIKV LRTLQQMLLK
     KTKYGDRGNQ LRKMLLQNYL QNRKSTSRGD LPDPMGTGLD PDWSAIAATQ CRLDKEGATK
     LVCDLITSTK NEKIFQESIG LAIRLLDGGN TEIQKSFHNL MMSDKKSERF FKVLHDRMKR
     AQQETKSTVA VNMNDLGSQP HEDREPVDPT TKGRVASFSI PGSSSRYSLG PSLRRGHEVS
     ERVQSNEMGT SVLIMQPILR FLQLLCENHN RDLQNFLRCQ NNKTNYNLVC ETLQFLDIMC
     GSTTGGLGLL GLYINEDNVG LVIQTLETLT EYCQGPCHEN QTCIVTHESN GIDIITALIL
     NDISPLCKYR MDLVLQLKDN ASKLLLALME SRHDSENAER ILISLRPQEL VDVIKKAYLQ
     EEERENSEVS PREVGHNIYI LALQLSRHNK QLQHLLKPVK RIQEEEAEGI SSMLSLNNKQ
     LSQMLKSSVP AQEEEEDPLA YYENHTSQIE IVRQDRSMEQ IVFPVPGICQ FLTEETKHRL
     FTTTEQDEQG SKVSDFFDQS SFLHNEMEWQ RKLRSMPLIY WFSRRMTLWG SISFNLAVFI
     NIIIAFFYPY MEGASTGVLD SPLISLLFWI LICFSIAALF TKRYSIRPLI VALILRSIYY
     LGIGPTLNIL GALNLTNKIV FVVSFVGNRG TFIRGYKAMV MDMEFLYHVG YILTSVLGLF
     AHELFYSILL FDLIYREETL FNVIKSVTRN GRSILLTALL ALILVYLFSI VGFLFLKDDF
     ILEVDRLPNN HSTASPLGMP HGAAAFVDTC SGDKMDCVSG VSVPEVLEED GELDSTERAC
     DTLLMCIVTV MNHGLRNGGG VGDILRKPSK DESLFPARVV YDLLFFFIVI IIVLNLIFGV
     IIDTFADLRS EKQKKEEILK TTCFICGLER DKFDNKTVSF EEHIKLEHNM WNYLYFIVLV
     RVKNKTDYTG PESYVAQMIK NKNLDWFPRM RAMSLVSNEG EGEQNEIRIL QDKLNSTMKL
     VSHLTGQLNE LKEQMTEQRK RRQRLGFVDV QNCMSR
//
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