ID A0A096NTQ7_PAPAN Unreviewed; 1255 AA.
AC A0A096NTQ7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Tubulin-specific chaperone D {ECO:0000256|ARBA:ARBA00015003};
GN Name=TBCD {ECO:0000313|Ensembl:ENSPANP00000016428.3};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000016428.3, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000016428.3, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000016428.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TBCD family.
CC {ECO:0000256|ARBA:ARBA00006853}.
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DR AlphaFoldDB; A0A096NTQ7; -.
DR STRING; 9555.ENSPANP00000016428; -.
DR Ensembl; ENSPANT00000026632.3; ENSPANP00000016428.3; ENSPANG00000018746.3.
DR eggNOG; KOG1943; Eukaryota.
DR GeneTree; ENSGT00390000017103; -.
DR HOGENOM; CLU_003043_0_0_1; -.
DR OMA; EPHEAWH; -.
DR Proteomes; UP000028761; Chromosome 17.
DR Bgee; ENSPANG00000018746; Expressed in thymus and 65 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0048487; F:beta-tubulin binding; IEA:Ensembl.
DR GO; GO:0005096; F:GTPase activator activity; IEA:Ensembl.
DR GO; GO:0048667; P:cell morphogenesis involved in neuron differentiation; IEA:Ensembl.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0031115; P:negative regulation of microtubule polymerization; IEA:Ensembl.
DR GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IEA:Ensembl.
DR GO; GO:0007021; P:tubulin complex assembly; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR033162; TBCD.
DR InterPro; IPR022577; Tubulin_specific_chaperoneD_C.
DR PANTHER; PTHR12658; BETA-TUBULIN COFACTOR D; 1.
DR PANTHER; PTHR12658:SF0; TUBULIN-SPECIFIC CHAPERONE D; 1.
DR Pfam; PF12612; TFCD_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000028761}.
FT DOMAIN 901..1087
FT /note="Tubulin-specific chaperone D C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12612"
SQ SEQUENCE 1255 AA; 139215 MW; DDEF1F661BD8C3F4 CRC64;
MALSDEPAAG GPEEEAEEET LVFRAALEAF GESAETRALL GRLREVHGGG VAREVALERF
RVIMDKYQEQ PHLLDPHLEW MMNLLLDIVQ DQTSPASLVH LAFKFLYIIT KVRGYKTFLS
LFPHEVADVE PVLDLVTDQN PKDHETWETR YMLLLWLSVT CLIPFDFSRL DGNLLTQPGQ
TRMSIMDRIL QIAESYLIVS DKARDAAAVL MSRFITRPDV KRSKMAEFLD WSLCNLASSS
FQTLQGVITM DGMLQALAQI FKHGKREDCL PYAATVLRCL DDCKLPESNQ TLLRKLGVKL
VQRLGLTFLK PRVAAWRYQR GCRSLAANLQ LLAQGQSEQK PLIPTEDADE DDDVPEGVES
VIEQLLVGLK DKDTVVRWSA AKGIGRMAGR LPKALADDVV GSVLDCFSFQ ETDKAWHGGC
LALAELGRRG LLLPSRLVDV VAVILKALTY DEKRGSCSVG TNVRDAACYV CWAFARAYEP
RELKPFVTAI SSALVIAAVF DRDINCRRAA SAAFQENVGR QGTFPHGIDI LTTADYFAVG
NRANCFLVIS VYIAGFPEYT QPMIDHLVTM KINHWDGVIR ELAVKALHNL TQRAPEYSAT
QVFPRLLSMT LSPDLHTRHG SILACAEVAY ALYKLAAQEN RPVTDHLDEQ AVQGLKQIHQ
QLYDRQLYRG LGGELMRQAV CVLIEKLSLS KMPFQGDTII DGWQWLINDT LGCLHLISSH
SRQQIKDAAV SALATLCSEY YMKEPGEADP AIQEKLITQY LAELRSPEEM TRCGFSLALG
ALPGFLLKGR LQQVLAGLRA VTHTSPEDVN FPESRRDGLK AIARICQTVG VKPGAPDEAV
CRENVSQIYS ALLGCMNDYT TDSRGDVGGW VRKAAMTGLM DVTLLLAQSQ PELIEAHICE
RIMCCVAQQA SEKIDRFRAH AISVFLTLLH FDSPPIPHVP HRGELEKLFP RSDVASVNWN
APSQAFSRIT QLLGLPTYRY PVLLGLVVSL GGLTESTVRH STQSLFEYMK GVQSDPQALG
SFSRTLLQIF EDNLLNDRVS LPLLKTLDHV LTHGCFDIFT TEEDHPFAVK LLALCKKEIK
NSKDVQKLLS AIPVFCEMVQ FPGNVRRSAL LQLCLLLCHR FPLIRKSTAS QVYETLLTYS
DVVGADVLDE VVTVLSDTAW DAELAVVREQ RNRLCDLLGV PRPQLVPQVT LSPAQHEAPV
LPRALECSGA SGCAQLLPVH PHGPFPRLMS GPLGLRDQQS CLLWPLPAPV GPCGI
//
