ID A0A096QFX2_MAIZE Unreviewed; 556 AA.
AC A0A096QFX2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Nucleobase-ascorbate transporter 3 {ECO:0000313|EMBL:ONM01645.1};
GN Name=100279038 {ECO:0000313|EnsemblPlants:Zm00001eb030300_P001};
GN ORFNames=ZEAMMB73_Zm00001d030868 {ECO:0000313|EMBL:ONM01645.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM01645.1};
RN [1] {ECO:0000313|EMBL:ONM01645.1, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb030300_P001,
RC ECO:0000313|Proteomes:UP000007305};
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM01645.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:Zm00001eb030300_P001}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb030300_P001};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CM007647; ONM01633.1; -; Genomic_DNA.
DR EMBL; CM007647; ONM01634.1; -; Genomic_DNA.
DR EMBL; CM007647; ONM01638.1; -; Genomic_DNA.
DR EMBL; CM007647; ONM01639.1; -; Genomic_DNA.
DR EMBL; CM007647; ONM01640.1; -; Genomic_DNA.
DR EMBL; CM007647; ONM01641.1; -; Genomic_DNA.
DR EMBL; CM007647; ONM01644.1; -; Genomic_DNA.
DR EMBL; CM007647; ONM01645.1; -; Genomic_DNA.
DR RefSeq; XP_008661403.1; XM_008663181.1.
DR RefSeq; XP_008661407.1; XM_008663185.1.
DR RefSeq; XP_008661411.1; XM_008663189.1.
DR RefSeq; XP_008661413.1; XM_008663191.1.
DR RefSeq; XP_008661418.1; XM_008663196.1.
DR RefSeq; XP_008661423.1; XM_008663201.1.
DR RefSeq; XP_008661427.1; XM_008663205.1.
DR RefSeq; XP_008661432.1; XM_008663210.1.
DR AlphaFoldDB; A0A096QFX2; -.
DR SMR; A0A096QFX2; -.
DR IntAct; A0A096QFX2; 18.
DR STRING; 4577.A0A096QFX2; -.
DR PaxDb; 4577-GRMZM2G041050_P01; -.
DR EnsemblPlants; Zm00001eb030300_T001; Zm00001eb030300_P001; Zm00001eb030300.
DR EnsemblPlants; Zm00001eb030300_T002; Zm00001eb030300_P002; Zm00001eb030300.
DR EnsemblPlants; Zm00001eb030300_T003; Zm00001eb030300_P003; Zm00001eb030300.
DR EnsemblPlants; Zm00001eb030300_T004; Zm00001eb030300_P004; Zm00001eb030300.
DR EnsemblPlants; Zm00001eb030300_T005; Zm00001eb030300_P005; Zm00001eb030300.
DR GeneID; 100279038; -.
DR Gramene; Zm00001eb030300_T001; Zm00001eb030300_P001; Zm00001eb030300.
DR Gramene; Zm00001eb030300_T002; Zm00001eb030300_P002; Zm00001eb030300.
DR Gramene; Zm00001eb030300_T003; Zm00001eb030300_P003; Zm00001eb030300.
DR Gramene; Zm00001eb030300_T004; Zm00001eb030300_P004; Zm00001eb030300.
DR Gramene; Zm00001eb030300_T005; Zm00001eb030300_P005; Zm00001eb030300.
DR KEGG; zma:100279038; -.
DR eggNOG; KOG1292; Eukaryota.
DR InParanoid; A0A096QFX2; -.
DR OMA; FMEHIGD; -.
DR OrthoDB; 345287at2759; -.
DR Proteomes; UP000007305; Chromosome 1.
DR ExpressionAtlas; A0A096QFX2; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015207; F:adenine transmembrane transporter activity; IEA:EnsemblPlants.
DR GO; GO:0015208; F:guanine transmembrane transporter activity; IEA:EnsemblPlants.
DR GO; GO:0015294; F:solute:monoatomic cation symporter activity; IEA:EnsemblPlants.
DR GO; GO:0015210; F:uracil transmembrane transporter activity; IEA:EnsemblPlants.
DR GO; GO:0098702; P:adenine import across plasma membrane; IEA:EnsemblPlants.
DR GO; GO:0098710; P:guanine import across plasma membrane; IEA:EnsemblPlants.
DR GO; GO:0035344; P:hypoxanthine transport; IEA:EnsemblPlants.
DR GO; GO:0098721; P:uracil import across plasma membrane; IEA:EnsemblPlants.
DR InterPro; IPR006043; NCS2.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR11119:SF29; NUCLEOBASE-ASCORBATE TRANSPORTER 3; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A096QFX2};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 556 AA; 60501 MW; 1C20AB14559EA78B CRC64;
MGETNELPPP PVAAPPPMMP MQSMMVGAGA IHPPHEQFHH LNYCVHSNPS WVQVAALAFL
HYLVMLGSTV MLATAIVPAM GGNAGDKARV IQSFLFMSGI NTLLQTLIGT RLPTVMNASF
AFVVPVLSIA KEIESNNFLN DHERFKHTMR TAQGALIVAS ILNMILGFST IWGAYAKKFS
PVIMTPVVCV VGLGLFQLGF PQVGKCVEIG LPMLILAVVV QQYVPNYFSY IHQRVTFLFE
RYSLLLCIGI VWAFAAILTA AGAYDHASPK TQQHCRTDKS FLMSSAPWIK IPLPFEWGPP
IFTAGHSFGM MGAVLVAAFE STGAHFATAR LAGATPPPAY VLSRSVGLQG IGMFLEGIFS
VPAGSSVSVE NIGLLGLTKV GSRRVIQIST GFMIFFSIFG KFGAFFASIP LPIFAAIYCI
LFGIVAAVGV SFMQFANKNS MRNIYIIGLS LFLGISVPQY FNGYTSSAGG HGPARTNAGW
FNDIINTVFA SGPTVALIVA SVLDNTLEFR GYEADRGLSW FQPFLRRHKG YSDPRNEEFY
SFPISVYDVI PDRFRR
//
