ID A0A097AVN4_9VIBR Unreviewed; 429 AA.
AC A0A097AVN4;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Guanine permease {ECO:0000313|EMBL:KJY68841.1};
DE SubName: Full=NCS2 family permease {ECO:0000313|EMBL:NOH37765.1};
GN ORFNames=F0224_23495 {ECO:0000313|EMBL:NOI78625.1}, F0267_05905
GN {ECO:0000313|EMBL:NOH37765.1}, TW71_20015
GN {ECO:0000313|EMBL:KJY68841.1};
OS Vibrio coralliilyticus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=190893 {ECO:0000313|EMBL:NOH37765.1, ECO:0000313|Proteomes:UP000577246};
RN [1] {ECO:0000313|EMBL:KJY68841.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S2052 {ECO:0000313|EMBL:KJY68841.1};
RX PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT bacteria.";
RL BMC Genomics 16:158-158(2015).
RN [2] {ECO:0000313|Proteomes:UP000528382, ECO:0000313|Proteomes:UP000577246}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AIC-5 {ECO:0000313|EMBL:NOI78625.1,
RC ECO:0000313|Proteomes:UP000528382}, and X00-12-4
RC {ECO:0000313|EMBL:NOH37765.1, ECO:0000313|Proteomes:UP000577246};
RA Kehlet-Delgado H., Mueller R.S.;
RT "Draft genome sequencing and comparative genomics of hatchery-associated
RT Vibrios.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC ECO:0000256|PIRNR:PIRNR005353}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NOH37765.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXXR01000021; KJY68841.1; -; Genomic_DNA.
DR EMBL; VTYS01000004; NOH37765.1; -; Genomic_DNA.
DR EMBL; VTXB01000017; NOI78625.1; -; Genomic_DNA.
DR RefSeq; WP_006957929.1; NZ_VTYS01000004.1.
DR STRING; 190893.BA953_12355; -.
DR GeneID; 66920131; -.
DR KEGG; vct:JV59_02365; -.
DR KEGG; vcy:IX92_11990; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000528382; Unassembled WGS sequence.
DR Proteomes; UP000577246; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR026033; Azg-like_bact_archaea.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PIRSF; PIRSF005353; PbuG; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 429 AA; 44838 MW; F4420BD32D858A19 CRC64;
MFEKIFKLSE HGTNVKTEII AGMTTFLTMA YIIFVNPAIL ADAGMDRGAV FVATCLAAAI
GCFIMGFVAN YPIAQAPGMG LNAFFTYAVV LGMGYTWQVA LAAVFVSGVL FILLSVFKIR
EWIINSIPLS LRTGISAGIG LFLAFIALKN AGIVVDNPAT LVSLGSITSL PAVLASIGFF
LTIALVHRGV KGAVMIAILA VTGLGLAFGD VQWGGIMSTP PSIAPTFMQL DFSAVFEIGM
ISVVFAFLFV DLFDTAGTLV GVSQKAGLMD KDGKIPRLNK ALLADSTATS VGALLGTSNT
TSYIESVSGV AAGGRTGLTA VVVGILFLLA LFFSPLAGMI PAYATAGALF YVAILMLSGL
VSIDWRDLTE AAPVVVTCLL MPLTFSIAEG ISLGFIAYAA IKLFSGKGRD VSLSVWVMSA
IFIFKYIVA
//
