ID A0A097R0A0_HAFAL Unreviewed; 430 AA.
AC A0A097R0A0;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000256|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000256|HAMAP-Rule:MF_00671,
GN ECO:0000313|EMBL:AIU72154.1};
GN ORFNames=AT03_06925 {ECO:0000313|EMBL:AIU72154.1};
OS Hafnia alvei FB1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Hafniaceae; Hafnia.
OX NCBI_TaxID=1453496 {ECO:0000313|EMBL:AIU72154.1, ECO:0000313|Proteomes:UP000029986};
RN [1] {ECO:0000313|EMBL:AIU72154.1, ECO:0000313|Proteomes:UP000029986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FB1 {ECO:0000313|EMBL:AIU72154.1,
RC ECO:0000313|Proteomes:UP000029986};
RX PubMed=25075225; DOI=10.1186/1757-4749-6-29;
RA Tan J.Y., Yin W.F., Chan K.G.;
RT "Gene clusters of Hafnia alvei strain FB1 important in survival and
RT pathogenesis: a draft genome perspective.";
RL Gut Pathog. 6:29-29(2014).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. TolB occupies a key intermediary
CC position in the Tol-Pal system because it communicates directly with
CC both membrane-embedded components, Pal in the outer membrane and TolA
CC in the inner membrane. {ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000256|ARBA:ARBA00009820,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
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DR EMBL; CP009706; AIU72154.1; -; Genomic_DNA.
DR RefSeq; WP_025800718.1; NZ_CP009706.1.
DR AlphaFoldDB; A0A097R0A0; -.
DR GeneID; 78449336; -.
DR KEGG; hav:AT03_06925; -.
DR PATRIC; fig|1453496.5.peg.1385; -.
DR eggNOG; COG0823; Bacteria.
DR HOGENOM; CLU_047123_0_0_6; -.
DR OrthoDB; 9802240at2; -.
DR Proteomes; UP000029986; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR NCBIfam; TIGR02800; propeller_TolB; 1.
DR PANTHER; PTHR36842; PROTEIN TOLB HOMOLOG; 1.
DR PANTHER; PTHR36842:SF1; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR SUPFAM; SSF52964; TolB, N-terminal domain; 1.
DR SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00671};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00671};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_00671};
KW Reference proteome {ECO:0000313|Proteomes:UP000029986};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_00671}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00671"
FT CHAIN 22..430
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00671"
FT /id="PRO_5008983342"
FT DOMAIN 24..122
FT /note="TolB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04052"
SQ SEQUENCE 430 AA; 46123 MW; ED01F8BB7085CFB3 CRC64;
MKQAFRVAMG LLILWASVLH AEVRIVITQG VDTARPIGVV PFKWMGPGSA PEDIGGIVAA
DLRNSGKFNP IDTNRMPQQP TTVAEVTPAA WTALGIDAVV VGQVQPSADG GYMVSYQMVD
TSGNPGSVLS QNQYKVTKQW LRYAAHTSSD EVFEKLTGIK GAFRTRIAYV VQTNGGQFPY
ELRVADYDGY NQFVVHRSPQ PLMSPAWSPD GSKLAYVTFE SGKSALVIQT LSNGAIRQVA
SFPRHNGAPS FSPDGSKLAF ALSKTGSLNL YVMDLGSGSI RQVTDGRSNN TEPSWFPDSQ
TLAFTSDQGG RPQIYKVNIN GGAPERLTWE GSQNQDGDVS SDGKFLVMVG TSGGSQHITK
LDLGSNANQV LTSTFLDETP SIAPNGTMVI YSSTQGLGSV LQLVSTDGRF KARLPATDGQ
VKFPAWSPYL
//
