ID A0A097ZPF8_9CIRC Unreviewed; 277 AA.
AC A0A097ZPF8;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Replication-associated protein {ECO:0000256|ARBA:ARBA00014531};
DE AltName: Full=ATP-dependent helicase Rep {ECO:0000256|ARBA:ARBA00030754};
DE AltName: Full=RepP {ECO:0000256|ARBA:ARBA00032243};
GN Name=Rep {ECO:0000313|EMBL:BAP81873.1};
OS Cyclovirus ZM36a.
OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes;
OC Cirlivirales; Circoviridae; Cyclovirus.
OX NCBI_TaxID=1506568 {ECO:0000313|EMBL:BAP81873.1, ECO:0000313|Proteomes:UP000137490};
RN [1] {ECO:0000313|Proteomes:UP000137490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sasaki M., Orba Y., Ueno K., Ishii A., Moonga L., Hang'ombe B.M.,
RA Mweene A.S., Ito K., Sawa H.;
RT "Metagenomic Analysis of Shrew Enteric Virome Reveals Novel Viruses Related
RT to Human Stool-Associated Viruses.";
RL J. Gen. Virol. 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|ARBA:ARBA00004147}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the nanoviruses/circoviruses replication-
CC associated protein family. {ECO:0000256|ARBA:ARBA00008545}.
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DR EMBL; AB937982; BAP81873.1; -; Genomic_DNA.
DR RefSeq; YP_009104366.1; NC_025476.1.
DR GeneID; 22157899; -.
DR KEGG; vg:22157899; -.
DR OrthoDB; 6978at10239; -.
DR Proteomes; UP000137490; Genome.
DR GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR Gene3D; 3.40.1310.20; -; 1.
DR InterPro; IPR000605; Helicase_SF3_ssDNA/RNA_vir.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003365; Viral_rep_N.
DR Pfam; PF00910; RNA_helicase; 1.
DR Pfam; PF02407; Viral_Rep; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Host nucleus {ECO:0000256|ARBA:ARBA00022562}.
FT DOMAIN 8..92
FT /note="Viral replication-associated protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02407"
FT DOMAIN 164..248
FT /note="Helicase superfamily 3 single-stranded DNA/RNA
FT virus"
FT /evidence="ECO:0000259|Pfam:PF00910"
SQ SEQUENCE 277 AA; 32367 MW; C712A5C3F3EF89B3 CRC64;
MANNSTVRRF CWTLNNYTED DVDVLQKDLA ELCKFAIFGR EICPTTGTKH LQGFCNLQRP
KRFNSIRQIF GGRAHIERAK GSDIENQEYC SKSGDVWQCG SPSTQGTRTD LQKVVSVIEG
GERDIKALAI QFPVAYIKYF KGIEQYIRVA HGNQERDFKT EVFYFWGSTG TGKSRKAREE
SRALGETYYK PRGEWWDGYT GQPCVVIDDF YGWIKYDELL KICDRYPYRV PVKGGYENFV
SKYIWITSER PLEEVYRFLA YDCSSLRRRL NKEIHFE
//
