ID A0A098M6W1_9BACL Unreviewed; 953 AA.
AC A0A098M6W1;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=3'-5' exonuclease DinG {ECO:0000256|HAMAP-Rule:MF_02206, ECO:0000256|RuleBase:RU364106};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_02206, ECO:0000256|RuleBase:RU364106};
GN Name=dinG {ECO:0000256|HAMAP-Rule:MF_02206,
GN ECO:0000256|RuleBase:RU364106};
GN ORFNames=PWYN_24820 {ECO:0000313|EMBL:KGE17783.1};
OS Paenibacillus wynnii.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=268407 {ECO:0000313|EMBL:KGE17783.1, ECO:0000313|Proteomes:UP000029734};
RN [1] {ECO:0000313|EMBL:KGE17783.1, ECO:0000313|Proteomes:UP000029734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18334 {ECO:0000313|EMBL:KGE17783.1,
RC ECO:0000313|Proteomes:UP000029734};
RA den Bakker H.C.;
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KGE17783.1, ECO:0000313|Proteomes:UP000029734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18334 {ECO:0000313|EMBL:KGE17783.1,
RC ECO:0000313|Proteomes:UP000029734};
RA Tsai Y.-C., Martin N., Korlach J., Wiedmann M.;
RT "Comparative genomics of the Paenibacillus odorifer group.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: 3'-5' exonuclease. {ECO:0000256|HAMAP-Rule:MF_02206,
CC ECO:0000256|RuleBase:RU364106}.
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily. Type 2 sub-
CC subfamily. {ECO:0000256|HAMAP-Rule:MF_02206,
CC ECO:0000256|RuleBase:RU364106}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGE17783.1}.
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DR EMBL; JQCR01000003; KGE17783.1; -; Genomic_DNA.
DR RefSeq; WP_036657090.1; NZ_JQCR01000003.1.
DR AlphaFoldDB; A0A098M6W1; -.
DR STRING; 268407.PWYN_24820; -.
DR eggNOG; COG1199; Bacteria.
DR eggNOG; COG2176; Bacteria.
DR OrthoDB; 9803913at2; -.
DR Proteomes; UP000029734; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06127; DEDDh; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR HAMAP; MF_02206; DinG_exonucl; 1.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR006310; DinG.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; TIGR01407; dinG_rel; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00479; EXOIII; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_02206};
KW Exonuclease {ECO:0000256|HAMAP-Rule:MF_02206,
KW ECO:0000256|RuleBase:RU364106}; Helicase {ECO:0000313|EMBL:KGE17783.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_02206};
KW Nuclease {ECO:0000256|HAMAP-Rule:MF_02206, ECO:0000256|RuleBase:RU364106};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_02206}; Reference proteome {ECO:0000313|Proteomes:UP000029734}.
FT DOMAIN 253..517
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT DOMAIN 762..939
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT MOTIF 469..472
FT /note="DEAH box"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02206"
FT BINDING 288..295
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02206"
SQ SEQUENCE 953 AA; 107297 MW; 39B3732C8F5DEB46 CRC64;
MKFAVLDFET TGTQSVGEII QVGLAIIEED LSISRVYGSF VKPAAPIPPF ITGLTGITDS
DVENAPELEE MMMELVPLLD DVVLVGHNVS FDFHFLQSAL DRCGYLPFQG RILDTIDFLK
ICFPSLTTYQ LGAVTSQFGL THERPHQADS DAHATALVLL KCLEELYSLP LLTIQRLSEL
FTESDGDMGW YFDGLLRERE METFQPEGDL TFYRQLALKI GDWNELALPR ADSHENPLEH
LSFTDYMSEV TKRLKETLPH YESREAQEIM FGEVMKALEE EKHLLIEAGT GTGKSLGYLL
PAIYQSVLTD QKVMVSTHTI NLQDQLRERD IPLLTQVVPF PFKAAIFKGR GHYLCLRKFE
HKINRRDFIS PREDIITSAQ MIVWLTQTES GDDEELNMGN RGGDFWETVA SDTDSCLGRS
CPWFRKCFYH RAKHEASIAD VVITNHSKLF ADVKAGHQLL PAYEHLVIDE AHHLEDVAGK
HLGMHMKHFT VVHTLSRLFK DSRNGQLPTL RQQLQSAGSE QASEWSLIID RIYSDLITVK
ETWDTLSEKL FGLLPERSDA GAGEAGQLVM RLLPGNKPKN WEELSTLESG MITTLSDALR
SGERMLNEMR DQEGQSSSDS LITDIGGLFK DLAAIRDNVR FFMGLNDENV VYWLEANGNY
RSKSLQLYAV PVDVSSQLKE LFFDKKKSIV LTSATLSVDK SFQFMIDNLG LNEAAENGRL
MTALLPSPFH YREQALLVIP RDFPSVKGSV GDARFVDTLV QSLAEAAVTT RGRMMVLFTS
YRMLRQVYDP LKEALSSQEI TVLGQGIEGG SRSKLIRRFQ DSNASVLLGT SSFWEGVDIP
GEALTCLAIV RLPFQPPNHP LAEAKSELLQ AQKKNPFMKL SVPQAVIRFK QGFGRLVRTA
QDKGIVIVYD TRVIESYYGK YFLYSLPGPK MEHMLTDQMV PRIAEWLEEG GVS
//
