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Database: UniProt
Entry: A0A098RIR5_9GAMM
LinkDB: A0A098RIR5_9GAMM
Original site: A0A098RIR5_9GAMM 
ID   A0A098RIR5_9GAMM        Unreviewed;       488 AA.
AC   A0A098RIR5;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 33.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=FP66_02700 {ECO:0000313|EMBL:KGE78657.1};
OS   Halomonas salina.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=42565 {ECO:0000313|EMBL:KGE78657.1, ECO:0000313|Proteomes:UP000029721};
RN   [1] {ECO:0000313|EMBL:KGE78657.1, ECO:0000313|Proteomes:UP000029721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIFRI 1 {ECO:0000313|EMBL:KGE78657.1,
RC   ECO:0000313|Proteomes:UP000029721};
RA   Behera B.D., Meena D.K., Das P., Maharana J., Paria P., Sharma A.P.,
RA   Shamsudheen K.V., Rijit J., Dixit V., Verma A., Scaria V.,
RA   Sivasubbu S.;
RT   "Draft genome sequence of an extremely salt tolerant bacteria
RT   Halomonas salina/CIFRI 1.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KGE78657.1}.
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DR   EMBL; JOKD01000014; KGE78657.1; -; Genomic_DNA.
DR   RefSeq; WP_035594567.1; NZ_JOKD01000014.1.
DR   EnsemblBacteria; KGE78657; KGE78657; FP66_02700.
DR   Proteomes; UP000029721; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029721};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029721}.
FT   DOMAIN      185    376       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      396    465       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     193    200       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      347    367       {ECO:0000256|SAM:Coils}.
FT   COILED      465    485       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   488 AA;  54700 MW;  13C8AFEC67FA2CC5 CRC64;
     MSLALWQQCL DTLQDELSSQ QFNTWIRPLQ AEEGEANQLR LLAPNRFVRD WVSDKYAKRI
     SELMRELSPA KPPKVVVTVG SRRAASPAPQ TRELGDPVSA APRAPAVQTP PRGDVADESE
     IDQLRDEGAE APRRPGSERQ VQVEGSLKHN SGLNPSFTFE TFVEGKSNQL ARAASRQVSE
     NPGGAYNPLF LYGGVGLGKT HLMHAVGNAL AGRRENARVV YLHSERFVAD MVKALQLNAI
     NDFKRFYRSV DALLIDDIQF FAGKERSQEE FFHTFNALLE GGQQMILTSD RYPKEISGVE
     ERLKSRFGWG LTVAIEPPEL ETRVAILMKK ADQAKVDLPH DAAFFIAQKI RSNVRELEGA
     LKKVIADSHF MGRPITQDFI RESLKDLLAL QDKQVGVDNI QRTVAEYYKI KLADLLSKRR
     SRSVARPRQV AMALAKELTN HSLPEIGDAF GGRDHTTVLH ACRKVQALQE ENADIREDYK
     NLLRLLTS
//
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