ID   A0A098S3R1_9BACT        Unreviewed;       613 AA.
AC   A0A098S3R1;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Peptidase M1 {ECO:0000313|EMBL:KGE86681.1};
GN   ORFNames=IX84_19555 {ECO:0000313|EMBL:KGE86681.1};
OS   Phaeodactylibacter xiamenensis.
OC   Bacteria; Bacteroidota; Saprospiria; Saprospirales; Haliscomenobacteraceae;
OC   Phaeodactylibacter.
OX   NCBI_TaxID=1524460 {ECO:0000313|EMBL:KGE86681.1, ECO:0000313|Proteomes:UP000029736};
RN   [1] {ECO:0000313|EMBL:KGE86681.1, ECO:0000313|Proteomes:UP000029736}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KD52 {ECO:0000313|EMBL:KGE86681.1,
RC   ECO:0000313|Proteomes:UP000029736};
RX   PubMed=25052393; DOI=10.1099/ijs.0.063909-0;
RA   Chen Z.Jr., Lei X., Lai Q., Li Y., Zhang B., Zhang J., Zhang H., Yang L.,
RA   Zheng W., Tian Y., Yu Z., Xu H.Jr., Zheng T.;
RT   "Phaeodactylibacter xiamenensis gen. nov., sp. nov., a member of the family
RT   Saprospiraceae isolated from the marine alga Phaeodactylum tricornutum.";
RL   Int. J. Syst. Evol. Microbiol. 64:3496-3502(2014).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|PIRSR:PIRSR634015-3};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR634015-3};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGE86681.1}.
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DR   EMBL; JPOS01000075; KGE86681.1; -; Genomic_DNA.
DR   RefSeq; WP_044224175.1; NZ_JPOS01000075.1.
DR   AlphaFoldDB; A0A098S3R1; -.
DR   STRING; 1524460.IX84_19555; -.
DR   OrthoDB; 9814383at2; -.
DR   Proteomes; UP000029736; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09604; M1_APN_like; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR034015; M1_LTA4H.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   PANTHER; PTHR45726; LEUKOTRIENE A-4 HYDROLASE; 1.
DR   PANTHER; PTHR45726:SF3; LEUKOTRIENE A-4 HYDROLASE; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR634015-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029736};
KW   Zinc {ECO:0000256|PIRSR:PIRSR634015-3}.
FT   DOMAIN          341..493
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
FT   ACT_SITE        350
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR634015-1"
FT   ACT_SITE        438
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR634015-1"
FT   BINDING         349
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR634015-3"
FT   BINDING         353
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR634015-3"
FT   BINDING         372
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR634015-3"
SQ   SEQUENCE   613 AA;  70589 MW;  B6563204DD75F55F CRC64;
     MKIWYSLFFC CITVAALQAQ PDRWQQAAKY TMDIDFDVKK HQFDGKQTLV YTNNSPDTLH
     RAFYHLYFNA FQPNSMMDVR SQNLKDSDPR VGGRIGELEP DEIGYHEINS LTVDGKKATF
     EVVGTILEVQ LPQPILPNSK AVFEMEFESQ VPVQIRRSGR DNAEGISYSM AQWYPKMAEY
     DYQGWHANPY VGREFYGIWG DFDVTIHIDS EYIIGATGYL QNPKEIGHGY TDKAVKVKKG
     KKLSWNFVAP DVHDFVWGAD PDYTHTTYER EDGMVMHFFY QENERTKENW EALPAIMDEA
     FAFINENYGQ YPYEQYSFIQ GGDGGMEYPM ATLITGERSL PSLVGVSVHE LMHSWYQMLL
     GTNEALYAWM DEGFTSWASS NVMNHLREKG LIPGEASDNP HLGSYMGYAN FSQSGLEEPL
     ITHSDHFNTN SAYGVASYVK GAVFLEQLKY IIGEDAFDQG MLRYFDTWKF KHPNSNDFIR
     IMEKQSMIEL DWYREYWINT THTIDYGIEN VKVDGRTAVA VLNRVGIIPM PVEVEVVLTD
     GTSKRILVPL RIMRGHKPLN DMELAEDWPW THPQYELDLG VKAKDIEKVV IDPDFGMADI
     DRENNTYEMI SDE
//