ID   A0A098S8J6_9BACT        Unreviewed;      1198 AA.
AC   A0A098S8J6;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE            EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN   ORFNames=IX84_11380 {ECO:0000313|EMBL:KGE87998.1};
OS   Phaeodactylibacter xiamenensis.
OC   Bacteria; Bacteroidota; Saprospiria; Saprospirales; Haliscomenobacteraceae;
OC   Phaeodactylibacter.
OX   NCBI_TaxID=1524460 {ECO:0000313|EMBL:KGE87998.1, ECO:0000313|Proteomes:UP000029736};
RN   [1] {ECO:0000313|EMBL:KGE87998.1, ECO:0000313|Proteomes:UP000029736}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KD52 {ECO:0000313|EMBL:KGE87998.1,
RC   ECO:0000313|Proteomes:UP000029736};
RX   PubMed=25052393; DOI=10.1099/ijs.0.063909-0;
RA   Chen Z.Jr., Lei X., Lai Q., Li Y., Zhang B., Zhang J., Zhang H., Yang L.,
RA   Zheng W., Tian Y., Yu Z., Xu H.Jr., Zheng T.;
RT   "Phaeodactylibacter xiamenensis gen. nov., sp. nov., a member of the family
RT   Saprospiraceae isolated from the marine alga Phaeodactylum tricornutum.";
RL   Int. J. Syst. Evol. Microbiol. 64:3496-3502(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC         N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC         COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC         Evidence={ECO:0000256|ARBA:ARBA00001279};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGE87998.1}.
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DR   EMBL; JPOS01000026; KGE87998.1; -; Genomic_DNA.
DR   RefSeq; WP_044220105.1; NZ_JPOS01000026.1.
DR   AlphaFoldDB; A0A098S8J6; -.
DR   STRING; 1524460.IX84_11380; -.
DR   REBASE; 100114; PxiKD52ORF11380P.
DR   OrthoDB; 32195at2; -.
DR   Proteomes; UP000029736; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR047939; BREX_1_PglX.
DR   InterPro; IPR046816; MmeI_Mtase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; NF033452; BREX_1_MTaseX; 1.
DR   PANTHER; PTHR33841:SF1; ADENINE-SPECIFIC METHYLTRANSFERASE PGLX; 1.
DR   PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR   Pfam; PF20473; MmeI_Mtase; 1.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029736};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          279..481
FT                   /note="MmeI-like DNA-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF20473"
SQ   SEQUENCE   1198 AA;  136569 MW;  9A90854A2F3CFC85 CRC64;
     MQTTTLKSFA QDARRKLIEQ ISNRLEQVLR TDSLEQRERK QQIDQLKRGL EEKGKAALVE
     EVAYTWFNRL VALRFMDAND YTRPRVLSPA DGETLPEILQ QAKRGLIEED LPVDRKRVLQ
     LLNGELPSAD PQNEAYQLLL IAACNQWHRA MPFMFPRLQD YTELLVPNDL LSARSIVQDV
     REGMSGTDAQ NVEIIGWLYQ FYISEKKDAV FAAKGRVAPA DLPAATQLFT PRWIVEYMVQ
     NTLGKLWLQN RPNSGLRAHM PYYIDSPAAQ AADFLRIESV TDIRFLDQAC GSGHILLYAF
     ELLTLMYEEE GYGKSEIPQL ILQHNLRGFE IDERAAQLAG FALMMKARGY HRRIFRKEAR
     PHILQFLDLP LSAEETAEAL QACGLQPSDA LRTDLEHLQQ ATNLGSLIQP QADAAEIGQA
     LKAVAQARAT NDVFLRTRLQ HLHTALQQLQ ELGQQVHCVV DNPPYMGGGN MNKALAKFVK
     QNYPASKSDL MACFMEGGLA MLHPGGYLGM INQHSWMFLS SYEKLREQLI QGTYFDTMLH
     LGPRAFPEIG GEVVQSTAFT FCNIPPMEEE GIYLRLTDFK SASQKEEEAA AAIETGDASE
     LWCHARQKDF QKIPGSPIGY WVSEKISKAF EEKKELGHYA WLKQGFKTGD NNQFLRYYYE
     CPEEKINKKW FLCNKGGEFR KWFGNVVHCV NWENNGFLIK NLFDENGKLR SRPQNEKYYF
     KEGISWTKIS SGLPSFRYSK ASYLFESNGS LLVSKQDVKL VYLIGLLNSN VTVELLRVVS
     PTLDYGEGAL SNLPVEEANS NEVQAIAQAC ISLSKSDWDS QETSWDFQRH PLLGGGVKSL
     SEAYATYQAH WREQFAQLHA QEEALNRIFI DLYGLQAELS PEVPLEDITI LQQELDRKAL
     KAATVKLSKR QDCPVGSAAR QQFVQDALVF DDTEVLAQFI SYAVGCMMGR YSLDKDGLIL
     ANAGEGLPEY WSKTGTSPDT ATFLPDEDGI IPLLAEDYFP DDVAGRFRRF LEAAFGPEQF
     EANLQFVEKA LGRDIRSYFV REFYKDHLKR YKKRPIYWLF SSPGKHFQTL VYVHRYRPDT
     VSRLLNDYVR DFIRKLEAQR ITLVEITLKA DGSPREQTQA QKDIDQIDTI LEDVRQYERD
     ILYPLAARKL PLDLDDGVLV NYNKMGRAVL TVTSLNDAKA RKKVESFDWV DFDWGVVV
//