ID A0A098VNX4_9MICR Unreviewed; 532 AA.
AC A0A098VNX4;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=DI09_14p340 {ECO:0000313|EMBL:KGG52651.1}, DI09_56p100
GN {ECO:0000313|EMBL:KGG50772.1};
OS Mitosporidium daphniae.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Mitosporidium.
OX NCBI_TaxID=1485682 {ECO:0000313|EMBL:KGG50772.1, ECO:0000313|Proteomes:UP000029725};
RN [1] {ECO:0000313|EMBL:KGG50772.1, ECO:0000313|Proteomes:UP000029725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UGP3 {ECO:0000313|EMBL:KGG50772.1,
RC ECO:0000313|Proteomes:UP000029725};
RC TISSUE=Spores {ECO:0000313|EMBL:KGG50772.1};
RA Haag K.L., James T.Y., Larsson R., Schaer T.M., Refardt D., Pombert J.-F.,
RA Ebert D.;
RT "A new species of microsporidia sheds light on the evolution of extreme
RT parasitism.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|RuleBase:RU004070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGG50772.1}.
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DR EMBL; JMKJ01000521; KGG50772.1; -; Genomic_DNA.
DR EMBL; JMKJ01000055; KGG52651.1; -; Genomic_DNA.
DR RefSeq; XP_013237199.1; XM_013381745.1.
DR RefSeq; XP_013239078.1; XM_013383624.1.
DR AlphaFoldDB; A0A098VNX4; -.
DR GeneID; 25258489; -.
DR GeneID; 25260335; -.
DR VEuPathDB; MicrosporidiaDB:DI09_14p340; -.
DR VEuPathDB; MicrosporidiaDB:DI09_56p100; -.
DR HOGENOM; CLU_000995_7_2_1; -.
DR OrthoDB; 1342623at2759; -.
DR Proteomes; UP000029725; Unassembled WGS sequence.
DR GO; GO:0031261; C:DNA replication preinitiation complex; IEA:UniProt.
DR GO; GO:0042555; C:MCM complex; IEA:UniProt.
DR GO; GO:0005656; C:nuclear pre-replicative complex; IEA:UniProt.
DR GO; GO:0043596; C:nuclear replication fork; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR GO; GO:0006279; P:premeiotic DNA replication; IEA:UniProt.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR018525; MCM_CS.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF26; DNA REPLICATION LICENSING FACTOR MCM7; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00847; MCM_1; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070};
KW Reference proteome {ECO:0000313|Proteomes:UP000029725}.
FT DOMAIN 165..355
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 532 AA; 58429 MW; 91B06328EC1DC4A4 CRC64;
MYVVMVANSG SGYGNFLGSG SCNARSSAFE ITSKGIGPFV ASLISCTCSA GRRAKHPIHA
AKAAHPALAN AQITDQVPIG HIPRSISVYL YEDLTRVASP GDEVILTGIF LPRAYTGYQA
IRAGLLTDTF VHAMSVELMI KKYSQLVLDP KVLVQVVALS KEPNVYSKLA RSIAPEIYGH
EDVKKALLLM MAGGVTKETA DGLRIRGNVH LRLLKYISRI APRGVYTTGK GSSGVGLTAA
VVKDPLTNEM VLVLADNGIC CIDEFDKMEE SDRTAIHEVM EQQTISISKA GITTTLNART
CILAAANPLH GRYNIRRSPN ENINLPYALL SRFDILFLLL DRPNVEEDAR LASHILNVHR
TGSVSCNEEG VDPSTFFVSP DVLRYYSFGL FFRQYIAYAR RFNPVLPKSL VEYLTGVYVS
LRTTDAMGKD FYTTPRTLTG VIRMSQALVD FLLQRYPADP ISKIYAIIRD LAKAIQTEYN
SGAPIQLPID IIRESIQSAG YSETQLQSCL SMFDRASVWS LSENGQRLVI LN
//
