ID   A0A098Y8Q9_9ACTN        Unreviewed;       359 AA.
AC   A0A098Y8Q9;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=IN07_09885 {ECO:0000313|EMBL:KGH46859.1};
OS   Modestobacter caceresii.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Modestobacter.
OX   NCBI_TaxID=1522368 {ECO:0000313|EMBL:KGH46859.1, ECO:0000313|Proteomes:UP000029713};
RN   [1] {ECO:0000313|EMBL:KGH46859.1, ECO:0000313|Proteomes:UP000029713}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KNN45-2b {ECO:0000313|EMBL:KGH46859.1,
RC   ECO:0000313|Proteomes:UP000029713};
RA   Bukarasam K., Bull A., Girard G., van Wezel G., Goodfellow M.;
RT   "Biosystematic studies on Modestobacter strains isolated from extreme
RT   hyper-arid desert soil and from historic building.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGH46859.1}.
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DR   EMBL; JPMX01000038; KGH46859.1; -; Genomic_DNA.
DR   RefSeq; WP_036335460.1; NZ_JPMX01000038.1.
DR   AlphaFoldDB; A0A098Y8Q9; -.
DR   STRING; 1522368.IN07_09885; -.
DR   OrthoDB; 9779574at2; -.
DR   Proteomes; UP000029713; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029713}.
FT   DOMAIN          15..349
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   359 AA;  38272 MW;  6E22519315875F81 CRC64;
     MPAAPLDVET LTRAPKVLLH DHLDGGLRPQ TVLELADEVG YRELPADEPE ALGRWFREAA
     DSGSLERYLL TFAHTVAVMQ RPEAVQRVAR ECALDLAADG VVYAEVRMAP ELLTAGGMSL
     DAAVEAMLDG YAQGSREAAA AGRPIVVGTL LCAMRQADRW VEVAEQVVRH RDAGVVGFDL
     AGPEDGFPPD RIPAAIELLD RAGAHRTIHA GEAAGIESIR AALDGAGAER LGHGVRIADE
     VPVDGPLGEL AERVRDEQVP LEVAPSSNVQ TGAYPTLADH PVDRLHRAGF AVTLNTDNRL
     MSGVSATSEL AAVVDTFGWG WDDVQAVAER ALRGGFADDA VRARVFTDVL RPGFEALRP
//