UniProt: A0A099I445

Database: UniProt
Entry: A0A099I445_CLOIN

LinkDB:  A0A099I445_CLOIN 
Original site:  A0A099I445_CLOIN

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Ontology (2)   
   GO (2)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (4)   
   EMBL (4)   
Protein domain (4)   
   InterPro (3)   
   Pfam (1)   
Literature (2)   
   PubMed (2)   
All databases (13)   

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ID   A0A099I445_CLOIN        Unreviewed;       293 AA.
AC   A0A099I445;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:KGJ52356.1, ECO:0000313|EMBL:QQR25315.1};
GN   ORFNames=ADH65_20545 {ECO:0000313|EMBL:ASU20699.1}, CIAN88_15035
GN   {ECO:0000313|EMBL:KGJ52356.1}, GT649_08145
GN   {ECO:0000313|EMBL:MZH59969.1}, I5Q87_15680
GN   {ECO:0000313|EMBL:QQR25315.1};
OS   Clostridium innocuum.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Coprobacillaceae; Thomasclavelia.
OX   NCBI_TaxID=1522 {ECO:0000313|EMBL:KGJ52356.1, ECO:0000313|Proteomes:UP000030008};
RN   [1] {ECO:0000313|EMBL:KGJ52356.1, ECO:0000313|Proteomes:UP000030008}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AN88 {ECO:0000313|EMBL:KGJ52356.1,
RC   ECO:0000313|Proteomes:UP000030008};
RA   Feng Y., Chiu C.-H.;
RT   "Clostridium innocuum, an unnegligible vancomycin-resistant pathogen
RT   causing extra-intestinal infections.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ASU20699.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=I46 {ECO:0000313|EMBL:ASU20699.1};
RX   PubMed=29051233;
RA   Garzetti D., Brugiroux S., Bunk B., Pukall R., McCoy K.D., Macpherson A.J.,
RA   Stecher B.;
RT   "High-Quality Whole-Genome Sequences of the Oligo-Mouse-Microbiota
RT   Bacterial Community.";
RL   Genome Announc. 5:e00758-17(2017).
RN   [3] {ECO:0000313|Proteomes:UP000214713}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=I46 {ECO:0000313|Proteomes:UP000214713};
RA   Garzetti D.;
RT   "High-quality whole genome sequences of the Oligo-Mouse-Microbiota.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:MZH59969.1, ECO:0000313|Proteomes:UP000478871}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BIOML-A13 {ECO:0000313|EMBL:MZH59969.1,
RC   ECO:0000313|Proteomes:UP000478871};
RX   PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA   Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA   Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA   Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA   Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA   Xavier R.J., Alm E.J.;
RT   "A library of human gut bacterial isolates paired with longitudinal
RT   multiomics data enables mechanistic microbiome research.";
RL   Nat. Med. 25:1442-1452(2019).
RN   [5] {ECO:0000313|EMBL:QQR25315.1, ECO:0000313|Proteomes:UP000595712}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=I46 {ECO:0000313|EMBL:QQR25315.1,
RC   ECO:0000313|Proteomes:UP000595712};
RA   Marbouty M., Lamy-Besnier Q., Debarbieux L., Koszul R.;
RT   "Closed and high quality bacterial genomes of the OMM12 community.";
RL   Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP022722; ASU20699.1; -; Genomic_DNA.
DR   EMBL; JQIF01000069; KGJ52356.1; -; Genomic_DNA.
DR   EMBL; WWTM01000013; MZH59969.1; -; Genomic_DNA.
DR   EMBL; CP065320; QQR25315.1; -; Genomic_DNA.
DR   RefSeq; WP_008818815.1; NZ_WWTY01000012.1.
DR   Proteomes; UP000030008; Unassembled WGS sequence.
DR   Proteomes; UP000214713; Chromosome.
DR   Proteomes; UP000478871; Unassembled WGS sequence.
DR   Proteomes; UP000595712; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR019614; SAM-dep_methyl-trfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43042; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43042:SF2; SAM-DEPENDENT METHYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF10672; Methyltrans_SAM; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:KGJ52356.1};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KGJ52356.1}.
FT   DOMAIN          55..203
FT                   /note="S-adenosylmethionine-dependent methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF10672"
SQ   SEQUENCE   293 AA;  33345 MW;  B9D26F132ED57A8E CRC64;
     MNQVAKHWKD YECIDAGSGE KLERWKDIIL RRPDPQVIWP MEENSMWNSP HAHYHRSKSG
     GGSWEYKKKF KDSWTVSYGD LRFKVSPTGF KHTGLFPEQA ANWDWMMDTI QGSGREDLRV
     LNLFAYTGGA TMACASAGAA EVVHVDASKG MVNWAKENMM LSHLENHKIR FIVDDVLKFV
     AREKRRGRTY HAIIMDPPSY GRGPNGEIWK IEEQLYPLIS ACMEILDENP LFFLVNSYTT
     GFPPTVLYNL LRTTVGKKHR DGQIDAGEIG LPITATDSVL PCGIYGKWVS SKR
//

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