ID   A0A099J069_9MICO        Unreviewed;       513 AA.
AC   A0A099J069;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=L-2,4-diaminobutyrate decarboxylase {ECO:0000313|EMBL:MBB5641255.1};
DE            EC=4.1.1.86 {ECO:0000313|EMBL:MBB5641255.1};
DE   SubName: Full=Pyridoxal-dependent decarboxylase {ECO:0000313|EMBL:KGJ71829.1};
GN   ORFNames=BJ997_001803 {ECO:0000313|EMBL:MBB5641255.1}, GY21_19505
GN   {ECO:0000313|EMBL:KGJ71829.1};
OS   Cryobacterium roopkundense.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Cryobacterium.
OX   NCBI_TaxID=1001240 {ECO:0000313|EMBL:KGJ71829.1, ECO:0000313|Proteomes:UP000029864};
RN   [1] {ECO:0000313|EMBL:KGJ71829.1, ECO:0000313|Proteomes:UP000029864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RuG17 {ECO:0000313|EMBL:KGJ71829.1,
RC   ECO:0000313|Proteomes:UP000029864};
RA   Sisinthy S.;
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:MBB5641255.1, ECO:0000313|Proteomes:UP000561726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21065 {ECO:0000313|EMBL:MBB5641255.1,
RC   ECO:0000313|Proteomes:UP000561726};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR602129-50, ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU000382}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGJ71829.1}.
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DR   EMBL; JPXF01000126; KGJ71829.1; -; Genomic_DNA.
DR   EMBL; JACHBQ010000001; MBB5641255.1; -; Genomic_DNA.
DR   RefSeq; WP_035840019.1; NZ_JPXF01000126.1.
DR   AlphaFoldDB; A0A099J069; -.
DR   STRING; 1001240.GY21_19505; -.
DR   eggNOG; COG0076; Bacteria.
DR   Proteomes; UP000029864; Unassembled WGS sequence.
DR   Proteomes; UP000561726; Unassembled WGS sequence.
DR   GO; GO:0033983; F:diaminobutyrate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   CDD; cd06450; DOPA_deC_like; 1.
DR   Gene3D; 3.90.1150.170; -; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR010977; Aromatic_deC.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR45677:SF8; CYSTEINE SULFINIC ACID DECARBOXYLASE; 1.
DR   PANTHER; PTHR45677; GLUTAMATE DECARBOXYLASE-RELATED; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   PRINTS; PR00800; YHDCRBOXLASE.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU000382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029864}.
FT   MOD_RES         321
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ   SEQUENCE   513 AA;  55933 MW;  06C275E198B5501B CRC64;
     MSVAHEIDPS RAATITKHLF NARNRDRYER EVLAGVAAVR AQLGRTVRPF TGITPQALQA
     SVGAVDLDAP LADPAAALEE VERLYLRDAV YFHDVKYAAH LNCPVVIPAL VGEAILSAVN
     SSMDTWDQSV GATLMERHLI QWTADRIGLG PAADGIFTSG GSQSNLQALL IARNRVHERL
     QIEGADADVR LPDTLSRLRI FSSAVSHFSI RTSAATLGLG YEAVVSVPVD ADRRMNVHAL
     RAAIADCLAS GNIPMAVVAT AGTTDFGSVD PLERIALTCR ENDVWLHVDA AYGGGLLTSH
     RHRGLLDGID KADSVTVDYH KTFFQPVSSS ALLLRDGAMF SHVTHHSDYL NPRSASLRVP
     NQVDKSIQTT RRFDALKLWL TLRTMGADGI GDLLDTVIDL TRATWQELSA ADDFEVVVEP
     VLSTLVFRYV PAGLPEQPEA RNDLIDRMNL AVRRAIFDSG EAVIAGTTVN GEHYLKVTLL
     NADTTPGDLR VIFDLIRWQG SRFMQSELEQ AHV
//