ID A0A099S885_9CLOT Unreviewed; 366 AA.
AC A0A099S885;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=2-hydroxyglutaryl-CoA dehydratase {ECO:0000313|EMBL:KGK88829.1};
GN ORFNames=DP68_05595 {ECO:0000313|EMBL:KGK88829.1};
OS Clostridium sp. HMP27.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1487921 {ECO:0000313|EMBL:KGK88829.1, ECO:0000313|Proteomes:UP000030009};
RN [1] {ECO:0000313|EMBL:KGK88829.1, ECO:0000313|Proteomes:UP000030009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMP27 {ECO:0000313|EMBL:KGK88829.1,
RC ECO:0000313|Proteomes:UP000030009};
RA Tan B.F., Foght J., Budwill K.;
RT "Draft genome sequence of Clostridium sp. HMP27 isolated from a coal
RT degrading methanogenic culture.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGK88829.1}.
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DR EMBL; JMFY01000012; KGK88829.1; -; Genomic_DNA.
DR RefSeq; WP_035307258.1; NZ_JMFY01000012.1.
DR AlphaFoldDB; A0A099S885; -.
DR STRING; 1487921.DP68_05595; -.
DR eggNOG; COG3581; Bacteria.
DR Proteomes; UP000030009; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.11900; -; 1.
DR InterPro; IPR018709; CoA_activase_DUF2229.
DR PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR PANTHER; PTHR32329:SF2; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR Pfam; PF09989; DUF2229; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030009}.
FT DOMAIN 11..73
FT /note="DUF2229"
FT /evidence="ECO:0000259|Pfam:PF09989"
SQ SEQUENCE 366 AA; 41027 MW; 86B347D38C7E0F3E CRC64;
MKVTFPQLGN TYFAVKAIFD DIGIEYILPP VSNKTCLEMG VKISPEEMCF PFKIMMGAYI
QSIENGADTI ILPGSCGPCR YGEYCELQMN ILRKLGYNVK FIVIDAPGGI GKDELLSRIA
EIGKYSKKSR NQKIVAVLKG YKIISLIDGL ERKARLLSGY EVSRGECKRL LRECKKKALS
ALGSKEMIKV LMEYKEKLDN VKLDKHRKPI KIAIIGEIYT ILEPFSNQYI EDKLMDMGIS
TQKSLTPSWW VKNTVLSPFK LNSINIRRAS KKYLPLYIGG HSRECVGEAV LAHKNGFDGA
VQILPMGCMP EIVSKSILPT IASDKNFPIM TLVVDEMTGQ AGFDTRIEAF ADLLERRRGN
NVLYGN
//
