ID A0A099T9U5_9RHOB Unreviewed; 605 AA.
AC A0A099T9U5;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Precorrin-3B methylase {ECO:0000313|EMBL:KGL01958.1};
GN ORFNames=PM04_05205 {ECO:0000313|EMBL:KGL01958.1};
OS Thalassobacter sp. 16PALIMAR09.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Thalassobacter.
OX NCBI_TaxID=1225651 {ECO:0000313|EMBL:KGL01958.1, ECO:0000313|Proteomes:UP000029829};
RN [1] {ECO:0000313|EMBL:KGL01958.1, ECO:0000313|Proteomes:UP000029829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16PALIMAR09 {ECO:0000313|EMBL:KGL01958.1,
RC ECO:0000313|Proteomes:UP000029829};
RA Mas-Llado M., Nogales B., Bosch R.;
RT "Draft genome sequence of Thalassobacter sp. 16PALIMAR09.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGL01958.1}.
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DR EMBL; JHAK01000002; KGL01958.1; -; Genomic_DNA.
DR RefSeq; WP_038004326.1; NZ_JHAK01000002.1.
DR AlphaFoldDB; A0A099T9U5; -.
DR OrthoDB; 9772960at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000029829; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR002750; CobE/GbiG_C.
DR InterPro; IPR036518; CobE/GbiG_C_sf.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF01890; CbiG_C; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KGL01958.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029829};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 49..128
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 203..320
FT /note="CobE/GbiG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01890"
FT DOMAIN 337..550
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 605 AA; 62964 MW; 35E5DB03096BD823 CRC64;
MALDPIVLCL NRAGEPTAHL IAQALGAPVH GRETRVDQAD VFFANALDHI RTLFAAGTPV
IGVCASGILI RAVAPLLVDK SIDPPLLSVS DDGAIVIPLL GGHRGANRLA ATIGDAIGAT
AAVTTAGDVA LGVALDAPPV GYRLANPEDA KTAMAALLSG DGATCLGAPL FDLPKGTAAT
IEVTEKPAQT GPERLVYHPQ TFALGVGCAR DADPTELWDN VQAAMAEADI APGAIASVNT
LDLKADEPAM NQLAERLGVP LRVYSAAELE AEAPRLANPS DVVFAEVGCH GVSEGAALAA
APDGALAVAK RKTANTTCAL VRNPVPITEH AGRSRGRLSI VGIGPGQATW RTPEVSKLVA
DAEELVGYGL YIDLLGPLGY GKARSDFPLG GEEARCRYAL EKAAEGRNVA LVCSGDAGIY
AMGALVFELL DRGADELGVS DAAKRVDIVC SPGVSALQGA AARAGAPLGH DFCAISLSDL
LTPREDIIKR LHAAAEGDFV IAFYNPVSQR RRTLLAEARD ILLQHRPPET PVMLASSLGR
PEEYIRYRRL DALEVDEVDM LTVVLIGSSH SKLAHLGEGP RMYTPRGYAR KIDGDLAQAT
KEGQG
//
