UniProt: A0A099WDJ4

Database: UniProt
Entry: A0A099WDJ4_9LIST

LinkDB:  A0A099WDJ4_9LIST 
Original site:  A0A099WDJ4_9LIST

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Ontology (2)   
   GO (2)   
DNA sequence (31)   
   EMBL (31)   
Protein domain (3)   
   InterPro (2)   
   Pfam (1)   
All databases (36)   

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ID   A0A099WDJ4_9LIST        Unreviewed;       321 AA.
AC   A0A099WDJ4;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Nickel/cobalt efflux system {ECO:0000256|RuleBase:RU362101};
GN   ORFNames=EP57_03730 {ECO:0000313|EMBL:KGL42583.1}, HB759_07655
GN   {ECO:0000313|EMBL:MBC1331810.1}, HB809_13795
GN   {ECO:0000313|EMBL:MBC1308778.1}, HB811_06860
GN   {ECO:0000313|EMBL:MBC1316486.1}, HB816_14765
GN   {ECO:0000313|EMBL:MBC1231714.1}, HB817_12395
GN   {ECO:0000313|EMBL:MBC1227891.1}, HB818_05980
GN   {ECO:0000313|EMBL:MBC1285297.1}, HB900_07225
GN   {ECO:0000313|EMBL:MBC1574248.1}, HB902_04520
GN   {ECO:0000313|EMBL:MBC1561323.1}, HB904_10535
GN   {ECO:0000313|EMBL:MBC1616628.1}, HB907_09005
GN   {ECO:0000313|EMBL:MBC1565543.1}, HBP98_04335
GN   {ECO:0000313|EMBL:MBC2371233.1}, HCA46_08520
GN   {ECO:0000313|EMBL:MBC1778879.1}, HCA52_11705
GN   {ECO:0000313|EMBL:MBC1794088.1}, HCA55_04365
GN   {ECO:0000313|EMBL:MBC1795946.1}, HCA67_09395
GN   {ECO:0000313|EMBL:MBC2067981.1}, HCA68_00665
GN   {ECO:0000313|EMBL:MBC1896168.1}, HCA78_00705
GN   {ECO:0000313|EMBL:MBC2002267.1}, HCA80_03905
GN   {ECO:0000313|EMBL:MBC2035345.1}, HCA81_14010
GN   {ECO:0000313|EMBL:MBC2022166.1}, HCB02_00335
GN   {ECO:0000313|EMBL:MBC2103405.1}, HCB06_15045
GN   {ECO:0000313|EMBL:MBC2117947.1}, HCB25_04665
GN   {ECO:0000313|EMBL:MBC2243349.1}, HCB29_01995
GN   {ECO:0000313|EMBL:MBC2161827.1}, HCB35_13630
GN   {ECO:0000313|EMBL:MBC2241514.1}, HCB83_05420
GN   {ECO:0000313|EMBL:MBC2304297.1}, HCC18_15200
GN   {ECO:0000313|EMBL:MBC2318195.1}, HCC36_01320
GN   {ECO:0000313|EMBL:MBC2291858.1}, HCJ43_01745
GN   {ECO:0000313|EMBL:MBC1973971.1}, HCJ81_05995
GN   {ECO:0000313|EMBL:MBC2310430.1}, HCX63_01615
GN   {ECO:0000313|EMBL:MBC2321968.1};
OS   Listeria booriae.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=1552123 {ECO:0000313|EMBL:KGL42583.1, ECO:0000313|Proteomes:UP000029844};
RN   [1] {ECO:0000313|EMBL:KGL42583.1, ECO:0000313|Proteomes:UP000029844}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FSL A5-0281 {ECO:0000313|EMBL:KGL42583.1,
RC   ECO:0000313|Proteomes:UP000029844};
RA   den Bakker H.C.;
RT   "Novel Listeriaceae from food processing environments.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000526161, ECO:0000313|Proteomes:UP000528739}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FSL L7-0025 {ECO:0000313|EMBL:MBC2321968.1,
RC   ECO:0000313|Proteomes:UP000585036}, FSL L7-0029
RC   {ECO:0000313|EMBL:MBC2318195.1, ECO:0000313|Proteomes:UP000576477},
RC   FSL L7-0035 {ECO:0000313|EMBL:MBC2304297.1,
RC   ECO:0000313|Proteomes:UP000526161}, FSL L7-0039
RC   {ECO:0000313|EMBL:MBC2310430.1, ECO:0000313|Proteomes:UP000565628},
RC   FSL L7-0051 {ECO:0000313|EMBL:MBC2291858.1,
RC   ECO:0000313|Proteomes:UP000543005}, FSL L7-0149
RC   {ECO:0000313|EMBL:MBC2241514.1, ECO:0000313|Proteomes:UP000553016},
RC   FSL L7-0153 {ECO:0000313|EMBL:MBC2243349.1,
RC   ECO:0000313|Proteomes:UP000550367}, FSL L7-0256
RC   {ECO:0000313|EMBL:MBC2161827.1, ECO:0000313|Proteomes:UP000528739},
RC   FSL L7-0335 {ECO:0000313|EMBL:MBC2103405.1,
RC   ECO:0000313|Proteomes:UP000565263}, FSL L7-0360
RC   {ECO:0000313|EMBL:MBC2117947.1, ECO:0000313|Proteomes:UP000529446},
RC   FSL L7-0385 {ECO:0000313|EMBL:MBC2022166.1,
RC   ECO:0000313|Proteomes:UP000587422}, FSL L7-0435
RC   {ECO:0000313|EMBL:MBC2002267.1, ECO:0000313|Proteomes:UP000546806},
RC   FSL L7-0459 {ECO:0000313|EMBL:MBC2035345.1,
RC   ECO:0000313|Proteomes:UP000591514}, FSL L7-0520
RC   {ECO:0000313|EMBL:MBC1973971.1, ECO:0000313|Proteomes:UP000587214},
RC   FSL L7-0587 {ECO:0000313|EMBL:MBC2067981.1,
RC   ECO:0000313|Proteomes:UP000573524}, FSL L7-0818
RC   {ECO:0000313|EMBL:MBC1896168.1, ECO:0000313|Proteomes:UP000578190},
RC   FSL L7-0978 {ECO:0000313|EMBL:MBC1794088.1,
RC   ECO:0000313|Proteomes:UP000539064}, FSL L7-0990
RC   {ECO:0000313|EMBL:MBC1795946.1, ECO:0000313|Proteomes:UP000548082},
RC   FSL L7-1017 {ECO:0000313|EMBL:MBC1778879.1,
RC   ECO:0000313|Proteomes:UP000547643}, FSL L7-1299
RC   {ECO:0000313|EMBL:MBC1616628.1, ECO:0000313|Proteomes:UP000574104},
RC   FSL L7-1385 {ECO:0000313|EMBL:MBC1574248.1,
RC   ECO:0000313|Proteomes:UP000571880}, FSL L7-1387
RC   {ECO:0000313|EMBL:MBC1561323.1, ECO:0000313|Proteomes:UP000541955},
RC   FSL L7-1427 {ECO:0000313|EMBL:MBC1565543.1,
RC   ECO:0000313|Proteomes:UP000586951}, FSL L7-1816
RC   {ECO:0000313|EMBL:MBC1316486.1, ECO:0000313|Proteomes:UP000543379},
RC   FSL L7-1825 {ECO:0000313|EMBL:MBC1308778.1,
RC   ECO:0000313|Proteomes:UP000571424}, FSL L7-1831
RC   {ECO:0000313|EMBL:MBC1231714.1, ECO:0000313|Proteomes:UP000585770},
RC   FSL L7-1833 {ECO:0000313|EMBL:MBC1331810.1,
RC   ECO:0000313|Proteomes:UP000532866}, FSL L7-1834
RC   {ECO:0000313|EMBL:MBC1227891.1, ECO:0000313|Proteomes:UP000588567},
RC   FSL L7-1836 {ECO:0000313|EMBL:MBC1285297.1,
RC   ECO:0000313|Proteomes:UP000588455}, and FSL L7-1850
RC   {ECO:0000313|EMBL:MBC2371233.1, ECO:0000313|Proteomes:UP000546244};
RA   Liao J., Wiedmann M.;
RT   "Soil Listeria distribution.";
RL   Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362101};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362101}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the NiCoT transporter (TC 2.A.52) family.
CC       {ECO:0000256|ARBA:ARBA00010892, ECO:0000256|RuleBase:RU362101}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGL42583.1}.
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DR   EMBL; JNFA01000011; KGL42583.1; -; Genomic_DNA.
DR   EMBL; JAAROK010000006; MBC1227891.1; -; Genomic_DNA.
DR   EMBL; JAARON010000008; MBC1231714.1; -; Genomic_DNA.
DR   EMBL; JAAROI010000003; MBC1285297.1; -; Genomic_DNA.
DR   EMBL; JAAROS010000006; MBC1308778.1; -; Genomic_DNA.
DR   EMBL; JAAROV010000002; MBC1316486.1; -; Genomic_DNA.
DR   EMBL; JAAROL010000002; MBC1331810.1; -; Genomic_DNA.
DR   EMBL; JAARRW010000002; MBC1561323.1; -; Genomic_DNA.
DR   EMBL; JAARRU010000002; MBC1565543.1; -; Genomic_DNA.
DR   EMBL; JAARRX010000003; MBC1574248.1; -; Genomic_DNA.
DR   EMBL; JAARSH010000006; MBC1616628.1; -; Genomic_DNA.
DR   EMBL; JAARUV010000002; MBC1778879.1; -; Genomic_DNA.
DR   EMBL; JAARVG010000010; MBC1794088.1; -; Genomic_DNA.
DR   EMBL; JAARVD010000002; MBC1795946.1; -; Genomic_DNA.
DR   EMBL; JAARWF010000001; MBC1896168.1; -; Genomic_DNA.
DR   EMBL; JAASWF010000001; MBC1973971.1; -; Genomic_DNA.
DR   EMBL; JAARWW010000001; MBC2002267.1; -; Genomic_DNA.
DR   EMBL; JAARWY010000007; MBC2022166.1; -; Genomic_DNA.
DR   EMBL; JAARWV010000001; MBC2035345.1; -; Genomic_DNA.
DR   EMBL; JAARWQ010000003; MBC2067981.1; -; Genomic_DNA.
DR   EMBL; JAARXL010000001; MBC2103405.1; -; Genomic_DNA.
DR   EMBL; JAARXI010000009; MBC2117947.1; -; Genomic_DNA.
DR   EMBL; JAARYE010000001; MBC2161827.1; -; Genomic_DNA.
DR   EMBL; JAARZA010000006; MBC2241514.1; -; Genomic_DNA.
DR   EMBL; JAARYY010000002; MBC2243349.1; -; Genomic_DNA.
DR   EMBL; JAARZT010000002; MBC2291858.1; -; Genomic_DNA.
DR   EMBL; JAARZW010000004; MBC2304297.1; -; Genomic_DNA.
DR   EMBL; JAASWV010000006; MBC2310430.1; -; Genomic_DNA.
DR   EMBL; JAARZZ010000010; MBC2318195.1; -; Genomic_DNA.
DR   EMBL; JAATOC010000001; MBC2321968.1; -; Genomic_DNA.
DR   EMBL; JAARMV010000001; MBC2371233.1; -; Genomic_DNA.
DR   eggNOG; COG3376; Bacteria.
DR   OrthoDB; 9776706at2; -.
DR   Proteomes; UP000029844; Unassembled WGS sequence.
DR   Proteomes; UP000526161; Unassembled WGS sequence.
DR   Proteomes; UP000528739; Unassembled WGS sequence.
DR   Proteomes; UP000529446; Unassembled WGS sequence.
DR   Proteomes; UP000532866; Unassembled WGS sequence.
DR   Proteomes; UP000539064; Unassembled WGS sequence.
DR   Proteomes; UP000541955; Unassembled WGS sequence.
DR   Proteomes; UP000543005; Unassembled WGS sequence.
DR   Proteomes; UP000543379; Unassembled WGS sequence.
DR   Proteomes; UP000546244; Unassembled WGS sequence.
DR   Proteomes; UP000546806; Unassembled WGS sequence.
DR   Proteomes; UP000547643; Unassembled WGS sequence.
DR   Proteomes; UP000548082; Unassembled WGS sequence.
DR   Proteomes; UP000550367; Unassembled WGS sequence.
DR   Proteomes; UP000553016; Unassembled WGS sequence.
DR   Proteomes; UP000565263; Unassembled WGS sequence.
DR   Proteomes; UP000565628; Unassembled WGS sequence.
DR   Proteomes; UP000571424; Unassembled WGS sequence.
DR   Proteomes; UP000571880; Unassembled WGS sequence.
DR   Proteomes; UP000573524; Unassembled WGS sequence.
DR   Proteomes; UP000574104; Unassembled WGS sequence.
DR   Proteomes; UP000576477; Unassembled WGS sequence.
DR   Proteomes; UP000578190; Unassembled WGS sequence.
DR   Proteomes; UP000585036; Unassembled WGS sequence.
DR   Proteomes; UP000585770; Unassembled WGS sequence.
DR   Proteomes; UP000586951; Unassembled WGS sequence.
DR   Proteomes; UP000587214; Unassembled WGS sequence.
DR   Proteomes; UP000587422; Unassembled WGS sequence.
DR   Proteomes; UP000588455; Unassembled WGS sequence.
DR   Proteomes; UP000588567; Unassembled WGS sequence.
DR   Proteomes; UP000591514; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015099; F:nickel cation transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR004688; Ni/Co_transpt.
DR   InterPro; IPR011541; Ni/Co_transpt_high_affinity.
DR   PANTHER; PTHR31611; HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1; 1.
DR   PANTHER; PTHR31611:SF0; HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1; 1.
DR   Pfam; PF03824; NicO; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362101};
KW   Nickel {ECO:0000256|ARBA:ARBA00022596};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029844};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362101};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362101};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362101}.
FT   TRANSMEM        7..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362101"
FT   TRANSMEM        35..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362101"
FT   TRANSMEM        78..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362101"
FT   TRANSMEM        112..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362101"
FT   TRANSMEM        176..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362101"
FT   TRANSMEM        204..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362101"
FT   TRANSMEM        252..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362101"
FT   TRANSMEM        295..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362101"
SQ   SEQUENCE   321 AA;  35305 MW;  940EA465EF3D8DD4 CRC64;
     MRKTTSIPLY ALLVVLIHIV AVVLLLIYVQ TTPALLASAI LAYSYGARHA FDADHIVAID
     NTVRKLVSRK TDGNGVGFFF SMGHSTVVIL MIFVLIWVTG KLTGKWAFIT DYGPAIGTVV
     AGTFLILIAI SNIISLRKLM AAERNGTGMD DALASRGFIV RLVEPLNKFV TKSWHIYPIG
     FLFGLGFDTA TEIGLITLSV QSSATVPAIG LLCLPLSFLA GMCLFDTLDS IIMSQTYGWA
     YDNHKRRYRY NVIVTVISVV SAVVVGGTIL MQFLLSYTDL NGAVVHFING IDFNGFGITL
     MLSFLLIWFC AMLIYRRQKR L
//

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