ID A0A099XLD3_9FLAO Unreviewed; 608 AA.
AC A0A099XLD3;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=PHEL85_3115 {ECO:0000313|EMBL:KGL58844.1};
OS Polaribacter sp. Hel1_85.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=1250005 {ECO:0000313|EMBL:KGL58844.1, ECO:0000313|Proteomes:UP000029991};
RN [1] {ECO:0000313|EMBL:KGL58844.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hel1_85 {ECO:0000313|EMBL:KGL58844.1};
RA Xing P., Hahnke R.L., Unfried F., Markert S., Huang S., Barbeyron T.,
RA Harder J., Becher D., Schweder T., Gloenk F.O., Amann R.I., Teeling H.;
RT "Niches of two polysaccharide-degrading Polaribacter strains isolated from
RT the North Sea during a spring diatom bloom.";
RL ISME J. 0:0-0(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGL58844.1}.
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DR EMBL; JPDS01000003; KGL58844.1; -; Genomic_DNA.
DR RefSeq; WP_036827214.1; NZ_JPDS01000003.1.
DR AlphaFoldDB; A0A099XLD3; -.
DR STRING; 1250005.PHEL85_3115; -.
DR eggNOG; COG3250; Bacteria.
DR OrthoDB; 9801077at2; -.
DR Proteomes; UP000029991; Unassembled WGS sequence.
DR GO; GO:0004566; F:beta-glucuronidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:KGL58844.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KGL58844.1};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..608
FT /note="Beta-glucuronidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001964963"
FT DOMAIN 35..209
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 213..305
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 310..604
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 608 AA; 70960 MW; BF0E74412B1195C1 CRC64;
MKLLSSLLFV SVFSILSNLA QEQLIQNVYL RESTSLNGMW KYIVDPYENG FYNYRLEPFE
KQEKPQKSAF FKNAKQEDKT ELLEYNFDKS DSISIPSDWN SQKENLFYYE GTVWFKKSFN
YNIKKENNRV FVHFGASNYE TDVYFNGEKL GKHIGGFTPF NYEITHLLQK KDNFLVVKVD
NKRKKEGVPT LNTDWWNYGG ITRDVKLIET SSTFINDYFI QLNKNDRNTI NGKIQLNGSD
ISSKEIQIKI PELKINKKIK TDKNGVTTFK ISSKKIKYWS NKNPHLYEVF LKINDDIIKD
KIGFRTIKTS GSSILLNDEK IYLKGISIHE ESPFRGGRGY TKKDSKKLLT WAKELGCNYV
RLAHYPHNEH MVRLADEMGI LVWEENPVYW TISWKNKETY NNAKNQLAEV ISRDKNRASV
IIWSMANETP TSNARNAFLT SLAEFTKKED PTRLISAALE QSDYKNSKTI RTINDDFADI
VDVLSFNQYI GWYDGLPEKT EKISWKITQN KPVLISEFGA GAKKGFYADK NTRWSEEFQE
EVYVKTLKML DKIDQLQGLS PWILVDFKSP RRVLPEIQDG YNRKGLISEK GEKKKAFFVL
QKFYNSKD
//
