ID   A0A099ZA73_TINGU        Unreviewed;       596 AA.
AC   A0A099ZA73;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=N-acetylserotonin O-methyltransferase-like {ECO:0000313|EMBL:KGL79369.1};
DE   Flags: Fragment;
GN   ORFNames=N309_01064 {ECO:0000313|EMBL:KGL79369.1};
OS   Tinamus guttatus (White-throated tinamou).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Tinamiformes; Tinamidae; Tinamus.
OX   NCBI_TaxID=94827 {ECO:0000313|EMBL:KGL79369.1, ECO:0000313|Proteomes:UP000053641};
RN   [1] {ECO:0000313|EMBL:KGL79369.1, ECO:0000313|Proteomes:UP000053641}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N309 {ECO:0000313|EMBL:KGL79369.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000256|ARBA:ARBA00001968};
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DR   EMBL; KL892041; KGL79369.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A099ZA73; -.
DR   STRING; 94827.A0A099ZA73; -.
DR   Proteomes; UP000053641; Unassembled WGS sequence.
DR   GO; GO:0047429; F:nucleoside triphosphate diphosphatase activity; IEA:InterPro.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   CDD; cd00555; Maf; 1.
DR   Gene3D; 3.90.950.10; -; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   HAMAP; MF_00528; Maf; 1.
DR   InterPro; IPR031725; ASMT_dimerisation.
DR   InterPro; IPR016461; COMT-like.
DR   InterPro; IPR029001; ITPase-like_fam.
DR   InterPro; IPR003697; Maf-like.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR00172; maf; 1.
DR   PANTHER; PTHR43213; BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR43213:SF5; BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED; 1.
DR   Pfam; PF16864; Dimerisation2; 1.
DR   Pfam; PF02545; Maf; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   SUPFAM; SSF52972; ITPase-like; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51683; SAM_OMT_II; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:KGL79369.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053641};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000313|EMBL:KGL79369.1}.
FT   DOMAIN          270..352
FT                   /note="Acetylserotonin O-methyltransferase dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF16864"
FT   DOMAIN          370..574
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
FT   REGION          200..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KGL79369.1"
FT   NON_TER         596
FT                   /evidence="ECO:0000313|EMBL:KGL79369.1"
SQ   SEQUENCE   596 AA;  66333 MW;  77A28783C1F5E596 CRC64;
     GLRFEIVPSW FKETLEKSSF AAPYEYAIET AKQKALEVAN RMHVKHLRTP DIVIGADTIV
     TVDEQILEKP VDKQDAYRML SRLSGKEHSV FTGVAIIHCS SKDNQLEMEV TDFYEETKVK
     FSDLSEELLW EYIHSGEPMD KAGGYGIQAL GGMLVEYVHG DFLNVVGFPL NHFCKKLVEL
     YCPPPKHSIQ HTKHDSIPSV DTFENLSDGE SESSHSAGHK GANKLDNSST HPSGPVYNSE
     DCYCVKTGFV VPSENQNGVL ENAAKVPSTI LELMDGFKAS KALFVASKLK VFDHLKEKGS
     LNAADIANEM GASLCGTERL LDACAALGLL KKTPQGYSNT DATNTYLTSD GKYSLHGYIM
     HSNDYTWPLF ANLEFAVKEG TRQNHRAFGK KMEDLFKEYY QNQEVKQRFM AAMHSIAHLT
     ARDVATAFDL SQFKSACDLG GCTGALAHEL VQIYPDMKVT IFDLPEVIAN SSSFQSSGKC
     TAPVTFVSGD FFEDNLPEVD LYILSRVLHD WPDEKIHMLL SKISSVCKPG NGLLVAELVL
     DEQKMHPPRA VLQSLSMTEG RQRSGSEYKQ LLEKFRFTNV QIKMTGNLLD AVLCFR
//