ID A0A099ZN04_TINGU Unreviewed; 342 AA.
AC A0A099ZN04;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 28-JUN-2023, entry version 21.
DE RecName: Full=26S proteasome non-ATPase regulatory subunit 13 {ECO:0000256|ARBA:ARBA00015732};
DE AltName: Full=26S proteasome regulatory subunit RPN9 {ECO:0000256|ARBA:ARBA00029749};
DE AltName: Full=26S proteasome regulatory subunit S11 {ECO:0000256|ARBA:ARBA00032323};
DE AltName: Full=26S proteasome regulatory subunit p40.5 {ECO:0000256|ARBA:ARBA00031303};
DE Flags: Fragment;
GN ORFNames=N309_10153 {ECO:0000313|EMBL:KGL82303.1};
OS Tinamus guttatus (White-throated tinamou).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Tinamiformes; Tinamidae; Tinamus.
OX NCBI_TaxID=94827 {ECO:0000313|EMBL:KGL82303.1, ECO:0000313|Proteomes:UP000053641};
RN [1] {ECO:0000313|EMBL:KGL82303.1, ECO:0000313|Proteomes:UP000053641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N309 {ECO:0000313|EMBL:KGL82303.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the 26S proteasome, a multiprotein complex
CC involved in the ATP-dependent degradation of ubiquitinated proteins.
CC This complex plays a key role in the maintenance of protein homeostasis
CC by removing misfolded or damaged proteins, which could impair cellular
CC functions, and by removing proteins whose functions are no longer
CC required. Therefore, the proteasome participates in numerous cellular
CC processes, including cell cycle progression, apoptosis, or DNA damage
CC repair. {ECO:0000256|ARBA:ARBA00002362}.
CC -!- SUBUNIT: Component of the 19S proteasome regulatory particle complex.
CC The 26S proteasome consists of a 20S core particle (CP) and two 19S
CC regulatory subunits (RP). The regulatory particle is made of a lid
CC composed of 9 subunits including PSMD13, a base containing 6 ATPases
CC and few additional components. {ECO:0000256|ARBA:ARBA00011441}.
CC -!- SIMILARITY: Belongs to the proteasome subunit S11 family.
CC {ECO:0000256|ARBA:ARBA00006207}.
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DR EMBL; KL895125; KGL82303.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A099ZN04; -.
DR STRING; 94827.A0A099ZN04; -.
DR Proteomes; UP000053641; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR035298; PSMD13.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10539; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; 1.
DR PANTHER; PTHR10539:SF0; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000313|EMBL:KGL82303.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053641}.
FT DOMAIN 123..304
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL82303.1"
FT NON_TER 342
FT /evidence="ECO:0000313|EMBL:KGL82303.1"
SQ SEQUENCE 342 AA; 39259 MW; 6B4C34D248DED85D CRC64;
YYLRLWHQLT LQVLDFVQDP CFAQGDGLIK LYENFISEFE HRVNPLSLVE IILHVVRQMT
DPTVALSFLE KTREKVKSSD EAVILCKTAI GALKLNIGDL QVTKETIEEV EEMLNNLPGV
TSVHSRFYDL SSKYYQTIGN HASYYKDALR FLGCIDVKDL PAVGHHKWIF SLLTLVLLGF
LQLMHPVLES LRNTDRQWLI DTLYAFNSGN VETFQALKSA WGQQPDLAAN EALLLQKIQL
LCLMEMTFTR PANHRQLTFE EIAKSAKVTV NEVELLVMKA LSVGLVKGSI DEVDKRVHMT
WVQPRVLDLQ QIKGMKDRLE FWCTDVRSME MLVEHQAHDI LT
//
