ID A0A099ZNM2_TINGU Unreviewed; 1419 AA.
AC A0A099ZNM2;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Brain-specific angiogenesis inhibitor 1 {ECO:0000313|EMBL:KGL83994.1};
DE Flags: Fragment;
GN ORFNames=N309_06740 {ECO:0000313|EMBL:KGL83994.1};
OS Tinamus guttatus (White-throated tinamou).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Tinamiformes; Tinamidae; Tinamus.
OX NCBI_TaxID=94827 {ECO:0000313|EMBL:KGL83994.1, ECO:0000313|Proteomes:UP000053641};
RN [1] {ECO:0000313|EMBL:KGL83994.1, ECO:0000313|Proteomes:UP000053641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N309 {ECO:0000313|EMBL:KGL83994.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL896973; KGL83994.1; -; Genomic_DNA.
DR STRING; 94827.A0A099ZNM2; -.
DR Proteomes; UP000053641; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro.
DR CDD; cd15990; 7tmB2_BAI1; 1.
DR Gene3D; 1.25.40.610; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 4.10.1240.10; GPCR, family 2, extracellular hormone receptor domain; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 5.
DR InterPro; IPR043838; AGRB_N.
DR InterPro; IPR032471; GAIN_dom_N.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR008077; GPCR_2_brain_angio_inhib.
DR InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR InterPro; IPR001879; GPCR_2_extracellular_dom.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR000203; GPS.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR12011:SF39; ADHESION G PROTEIN-COUPLED RECEPTOR B1; 1.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF19188; AGRB_N; 1.
DR Pfam; PF16489; GAIN; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF02793; HRM; 1.
DR Pfam; PF00090; TSP_1; 5.
DR PRINTS; PR01694; BAIPRECURSOR.
DR PRINTS; PR00249; GPCRSECRETIN.
DR PRINTS; PR01705; TSP1REPEAT.
DR SMART; SM00303; GPS; 1.
DR SMART; SM00008; HormR; 1.
DR SMART; SM00209; TSP1; 5.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 5.
DR PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
DR PROSITE; PS50092; TSP1; 5.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000053641};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 889..915
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 927..946
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 958..976
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 997..1016
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1036..1059
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1080..1102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1108..1132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 520..590
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT DOMAIN 892..1133
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 276..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1360..1419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1360..1407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL83994.1"
FT NON_TER 1419
FT /evidence="ECO:0000313|EMBL:KGL83994.1"
SQ SEQUENCE 1419 AA; 158212 MW; 9C8655F7B28B75BA CRC64;
CTTLVQGKFF GYFSSFAVFP LNSSICSWII QNPDPRRYTL YMKILKPTSV CDYQHIRTYQ
FDSFLESTRT YLGMESFDDV LKLCDGSTRY AFLQSNKQFL QMKQTTPPGL ESGPMQWKPM
KAQERDFSVE YLVVGNRNPS KAACQMLCKW LDACLAISSS SHPCGIMQTP CSCSGGEVLD
QASEIPGFTK KKEDCYKDGI YLENCMSSPK DSSGVESLGG WKPWSAWGDC TKDCGGGLQT
RMRTCKPLPN EGLACVGVLE EGRLCNRKAC NTNGRYNSRS QSLRSTDNRK REDTDDLQHY
GYPAPQIGDP AAEEWSPWSV CSTTCGEGWQ TRTRFCVSSS YSTQCSGPLR EQRQCNNSAV
CPVHGTWDEW SPWSLCSSTC GRGYRDRTRT CKPPQFGGNP CEGPEKQTKF CNIALCPVDG
NWNEWSSWSS CSASCSNGTQ QRTRECNGPS YGGAECQGHW VETRDCFLRQ CPVDGKWQAW
GVWGSCTTTC GGGTQRRDRV CYGPFFGGAT CQGPKEEYKQ CNDKKCPEPH EICDEENFAS
VVWKETPAGD AAAVRCPRNA TGLILRRCTL DEEGIAYWDP PTYIKCVSID YRNIQMMTRE
HLSKAQRGLM GDGLSDVLQN LVEISQDGTS YSGDLLSTID VLRNMTEIFR RAYYSPTSGD
VQNFVQIISN LLSEENRDKW EEAQLTGPNA KELFRLVEDF IDVIGFRMKD FRDSYQVTDN
LVLSIHKLPA HAATDITFPM KGWRGMVDWA KNSEDKVTIS KSILSSGLAV TDDSSVFVVG
TVLYRNIGSI LSLQRNSTVV NSKVISVTVK PFPRSLLTPL EIEFSHLYNG TTNQTCILWD
EADRPRGPCS WRGCRTVPLD SFRTKCLCDR LATFAILAQL SPDMNMEKVL VPSVTLIVGC
GVSSLTLLLL IIIYVSVWRY IRSERSVILI NFCLSIISSN ALILIGQTQT RNKVICTLVA
AFLHFFFLSS FCWVLTEAWQ SYMAVTGRLR NRIIRKRFLC LGWGLPALVV AISVGFTKAK
GYGTVNYCWL SLEGGLLYAF VGPAAAVVLV NMVIGILVFN KLVSKDGITD KKLKERAGAS
LWSSCVVLPL LALTWMSAVL AITDRRSALF QILFAVFDSL EGFVIVMVHC ILRREVQDAV
KCRVVDRQEE GNGDSGGSFQ NGHAQLMTDF EKDVDMACRS VLNKDITTCR TSTITGTLKR
PSLQDEEKLK LNHQKGSSNF NSLPANVSKM HLQGSPHYLG AINLNEFSNH TLTLKKDKNQ
PPKSIYICDG DIFKKLDSEL SRAQEQTLDT SYVILPTNTS TLRAKPPKDE SKYSINIDQM
PQTRLIHLSM ATDPGFVVKS PPREPVTMTC SEVQGSSMIQ QQQQLPPPNI SNETQIPNSL
CDTGDSGNSG VVSKSETVST LSMSSLERRK SRYAELDFE
//
