ID A0A099ZUD2_CHAVO Unreviewed; 348 AA.
AC A0A099ZUD2;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 13-SEP-2023, entry version 21.
DE RecName: Full=Adenosine deaminase {ECO:0000256|ARBA:ARBA00018099};
DE EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
DE Flags: Fragment;
GN ORFNames=N301_06935 {ECO:0000313|EMBL:KGL85894.1};
OS Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL85894.1, ECO:0000313|Proteomes:UP000053858};
RN [1] {ECO:0000313|EMBL:KGL85894.1, ECO:0000313|Proteomes:UP000053858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL85894.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Cell junction {ECO:0000256|ARBA:ARBA00004282}.
CC Cell membrane {ECO:0000256|ARBA:ARBA00004296}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004296}; Extracellular side
CC {ECO:0000256|ARBA:ARBA00004296}. Cytoplasmic vesicle lumen
CC {ECO:0000256|ARBA:ARBA00004321}.
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR EMBL; KL869745; KGL85894.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A099ZUD2; -.
DR STRING; 50402.A0A099ZUD2; -.
DR Proteomes; UP000053858; Unassembled WGS sequence.
DR GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-SubCell.
DR GO; GO:0060205; C:cytoplasmic vesicle lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046936; F:2'-deoxyadenosine deaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
DR CDD; cd01320; ADA; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR006650; A/AMP_deam_AS.
DR InterPro; IPR001365; A_deaminase_dom.
DR InterPro; IPR006330; Ado/ade_deaminase.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR01430; aden_deam; 1.
DR PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR Pfam; PF00962; A_deaminase; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR PROSITE; PS00485; A_DEAMINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053858}.
FT DOMAIN 2..339
FT /note="Adenosine deaminase"
FT /evidence="ECO:0000259|Pfam:PF00962"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL85894.1"
FT NON_TER 348
FT /evidence="ECO:0000313|EMBL:KGL85894.1"
SQ SEQUENCE 348 AA; 39571 MW; 0BD50ED4291D5488 CRC64;
QVELHVHLDG AIRPETILHF GRKRGVPLPG STVDDLLKHV SYKTPLTLTQ FLEKFNHYMP
AIAGDREAVR RIAYELVETK AKEGVIYVEV RYSPHLLANC RVDPIPWGQT EGDLTPDEVV
NLVNQGLQDG ERDFRIKARS ILCCMRHMPS WSPEVVELCK KYQNNSVVAI DLAGDETLKV
ENTSEHKKAY EEAERCGIHR TVHAGEAGPP AMIKEAVYLL KAERIGHGYH VLEDPELYKE
LLRAKMHFEV CPWSSYLTGA CLPDFGKHPV AQFRKDRANY SINTDDPLIF NSNINKDYSI
VKDYMGFTEE DFKRVNINAA QSSFLPEKEK QELLNTLYEA YGMVPNAS
//
