ID A0A0A0A6B0_CHAVO Unreviewed; 1594 AA.
AC A0A0A0A6B0;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Low-density lipoprotein receptor-related protein 6 {ECO:0000313|EMBL:KGL88953.1};
DE Flags: Fragment;
GN ORFNames=N301_16304 {ECO:0000313|EMBL:KGL88953.1};
OS Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL88953.1, ECO:0000313|Proteomes:UP000053858};
RN [1] {ECO:0000313|EMBL:KGL88953.1, ECO:0000313|Proteomes:UP000053858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL88953.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; KL870627; KGL88953.1; -; Genomic_DNA.
DR STRING; 50402.A0A0A0A6B0; -.
DR Proteomes; UP000053858; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042813; F:Wnt receptor activity; IEA:InterPro.
DR GO; GO:0017147; F:Wnt-protein binding; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 3.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 4.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR017049; LRP5/6.
DR PANTHER; PTHR46513:SF40; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6; 1.
DR PANTHER; PTHR46513; VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED; 1.
DR Pfam; PF14670; FXa_inhibition; 4.
DR Pfam; PF00057; Ldl_recept_a; 3.
DR Pfam; PF00058; Ldl_recept_b; 11.
DR PIRSF; PIRSF036314; LDL_recpt-rel_p5/6; 1.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00192; LDLa; 3.
DR SMART; SM00135; LY; 20.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR SUPFAM; SSF63825; YWTD domain; 4.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 3.
DR PROSITE; PS51120; LDLRB; 15.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000313|EMBL:KGL88953.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KGL88953.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053858};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1356..1376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 45..88
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 89..131
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 132..175
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 176..218
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 267..306
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REPEAT 354..396
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 397..439
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 440..483
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 484..526
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 573..610
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REPEAT 656..698
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 699..741
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 742..784
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 825..867
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 874..912
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REPEAT 1008..1050
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1051..1095
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1096..1138
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 1188..1232
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REGION 1439..1477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1535..1594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1447..1463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1252..1267
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1270..1282
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1277..1295
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1289..1304
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1308..1320
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1315..1333
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1327..1342
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL88953.1"
FT NON_TER 1594
FT /evidence="ECO:0000313|EMBL:KGL88953.1"
SQ SEQUENCE 1594 AA; 178220 MW; BA71D5FA7018DE87 CRC64;
AAPLLLYANR RDLRLVDAAN GKENATVIVG GLEDAAAVDF VFVKGLIYWS DVSEEAIKRT
QFNKSGSVQN VVISGLLSPD GLACDWLGEK LYWTDSETNR IEVSNLDGSL RKVLFWQELD
QPRAIALDPA RGFMYWTDWG EVPKIERAGM DGSSRSIIVN TDIYWPNGLT LDYEEQKLYW
ADAKLNFIHK SNLDGSHRQA VVKGSLPHPF ALTLFGDTLY WTDWNTHSIL ACSKYSGEDL
REIHSNIFSP MDIHAFSQKR QPNATNPCGI NNGGCSHLCL MSPTKPSYQC ACPTGVKLLE
NGKTCKDGAT ELLLLARRTD LRRISLDTPD FTDIVLPLED IRHAIAIDFD PLEGYIYWTD
DEVRAIRRSF IDGSGSQFVV TAQIAHPDGI AVDWVARNLY WTDTGTDRIE VTRLNGTMRK
ILISEDLEEP RAIVLDPMVG YMYWTDWGEI PKIERAALDG SDRIVLVNTS LGWPNGLALD
YAESKIYWGD AKTDKIEVMN ADGTGRRVLV EDKLPHIFGF TLLGDYVYWT DWQRRSIERV
HKRTAEREII IDQLPDLMGL KATNVRQIIG TNPCAEDNGG CSHLCLYRPQ GLRCACPIGL
ELINDMKTCI VPEAFLLFSR RADIRRISLE TNNNNVAIPL TGVKEASALD FDVTDNRIYW
TDISLKTISR AFMNGSALEH VVEFGLDYPE GMAVDWLGKN LYWADTGTNR IEVSKLDGQH
RQVLVWKDLD SPRALALDPA EGFMYWTEWG GKPKIDRAAM DGTERTTLVP NVGRANGLTI
DYAKRRLYWT DLDTNLIESS NMLGLDREII ADDLPHPFGL TQYQDYIYWT DWSRRSIERA
NKTSGQNRTI IQGHLDYVMD ILVFHSSRQA GWNECASSNG HCSHLCLAVP VGGFVCGCPA
HYSLNSDNRT CSAPTTFLLF SQKNAINRMV IDEQQSPDII LPIHSLRNVR AIDYDPLDKQ
LYWIDSRQNI IRKAQEDGSQ SLTVVTSPVP NQNLDMQPYD LSIDIYSRYI YWTCEATNVI
NVTRLDGRPM GVVLKGDQDR PRAIVVNPEK GYMYFTNLQE RSPKIERAAL DGTEREVLFF
SGLSKPIALA IDSQLGKLFW ADSDLRRIES SDLSGANRIV LEDSNILQPV GLTVFENWLY
WIDRQQQMIE KIDMTGREGR TKVQARIAQL SDIHAVKELN IQEYRQHPCS QDNGGCSHIC
IVKGDGTTRC SCPVHLVLLQ DELSCGEPPT CSPQQFTCFT GEIDCIPVAW RCDGFTECED
HSDEKNCPVC SDTQFQCESG QCIDSALRCN GEANCQDNSD EKNCEVLCLT DQFRCASGQC
IGKSKKCDHN LDCNDSSDEQ GCYTTEEPAP QPNNTIGSII GVILTVFVVG AMYFICQRVL
CPRMKGDGET MTNDYVVHGP ASVPLGYVPH PSSLSGSLPG MSRGKSVISS LSIMGGSSGP
PYDRAHVTGA SSSSSSSTKG TYFPPILNPP PSPATERSHY TMEFGYSSNS PSTHRSYSYR
PYSYRHFAPP TTPCSTDVCD SDYAPSRRVT AATAKGYTSD LNYDSEPVPP PPTPRSQYLS
AEENYESCPP SPYTERSYSH HLYPPPPSPC TDSS
//
