ID   A0A0A0AEB5_CHAVO        Unreviewed;       586 AA.
AC   A0A0A0AEB5;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Growth factor receptor-bound protein 10 {ECO:0000313|EMBL:KGL92282.1};
GN   ORFNames=N301_00415 {ECO:0000313|EMBL:KGL92282.1};
OS   Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX   NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL92282.1, ECO:0000313|Proteomes:UP000053858};
RN   [1] {ECO:0000313|EMBL:KGL92282.1, ECO:0000313|Proteomes:UP000053858}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL92282.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GRB7/10/14 family.
CC       {ECO:0000256|ARBA:ARBA00006708}.
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DR   EMBL; KL871466; KGL92282.1; -; Genomic_DNA.
DR   RefSeq; XP_009882092.1; XM_009883790.1.
DR   RefSeq; XP_009882093.1; XM_009883791.1.
DR   AlphaFoldDB; A0A0A0AEB5; -.
DR   STRING; 50402.A0A0A0AEB5; -.
DR   GeneID; 104285342; -.
DR   KEGG; cvf:104285342; -.
DR   CTD; 2887; -.
DR   OrthoDB; 3144731at2759; -.
DR   Proteomes; UP000053858; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01259; PH_APBB1IP; 1.
DR   CDD; cd16141; RA_GRB10; 1.
DR   CDD; cd10415; SH2_Grb10; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR015042; BPS-dom.
DR   InterPro; IPR039664; GRB/APBB1IP.
DR   InterPro; IPR035037; Grb10_SH2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR039665; PH_APBB1IP.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR11243; GROWTH FACTOR RECEPTOR-BOUND PROTEIN; 1.
DR   PANTHER; PTHR11243:SF4; GROWTH FACTOR RECEPTOR-BOUND PROTEIN 10; 1.
DR   Pfam; PF08947; BPS; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00314; RA; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Receptor {ECO:0000313|EMBL:KGL92282.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053858};
KW   SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW   ProRule:PRU00191}.
FT   DOMAIN          166..250
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          292..401
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          485..581
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          86..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..111
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   586 AA;  66657 MW;  93D84FA3F64F698D CRC64;
     MALAGCPDSF LHLPYRIDNV DQTSAHGRRD LVEPGFQEPS NRISLNHQDD DVDLEALVND
     MNSSFESLYS TCSMQSETTP LLQNGQLNRS QLPSSGSGAL QPMSPRQKVQ RSQPVRIMAV
     RRLQEEEQQF RTSSLPAIPN PFPELCSPAS SPVLAPGSLP QSQPASKHDV KVFSEDGTSK
     VVEILADMTA RDLCQLLVYK SHCVDDNSWT LVEHHPHLGL ERCLEDHELI VQVESTMGSE
     SKFLFRKNYA KYEFFKNPMN FFPEQMVAWC QQTNGSIPQS QLLQNFLNSS SCPEIQGFLH
     VKELGRKSWK KLYVCLRRSG LYCSTKGTSK EPRHLQLLAD LEDSNIFSLI AGKKLYSAPA
     EYGFCIKPNR VRNETKELRL LCAEDEQSRT CWMTAFRLLK YGMLLYQNYR IPQQRKAMLP
     HFATPVRSVS ENSLVAMDFS AEALSAALEE GHAWRKRSTR MNILGSQSPL HPSTLSTVIH
     RTQHWFHGRI SREESHRIIK QQGLVDGLFL LRDSQSNPKA FVLTLCHHQK IKHFQILPCE
     DDGQIFFSLD DGNTKFSDLI QLVEFYQLNK GVLPCKLKHH CIRVAL
//