ID A0A0A0AJC2_CHAVO Unreviewed; 593 AA.
AC A0A0A0AJC2;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ferric-chelate reductase 1 {ECO:0000313|EMBL:KGL93135.1};
GN ORFNames=N301_03496 {ECO:0000313|EMBL:KGL93135.1};
OS Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL93135.1, ECO:0000313|Proteomes:UP000053858};
RN [1] {ECO:0000313|EMBL:KGL93135.1, ECO:0000313|Proteomes:UP000053858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL93135.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme b; Xref=ChEBI:CHEBI:60344;
CC Evidence={ECO:0000256|ARBA:ARBA00001970};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FRRS1 family.
CC {ECO:0000256|ARBA:ARBA00009195}.
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DR EMBL; KL871737; KGL93135.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A0AJC2; -.
DR STRING; 50402.A0A0A0AJC2; -.
DR Proteomes; UP000053858; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08760; Cyt_b561_FRRS1_like; 1.
DR CDD; cd09628; DOMON_SDR_2_like; 1.
DR CDD; cd08544; Reeler; 1.
DR Gene3D; 1.20.120.1770; -; 1.
DR Gene3D; 2.60.40.4060; Reeler domain; 1.
DR InterPro; IPR006593; Cyt_b561/ferric_Rdtase_TM.
DR InterPro; IPR005018; DOMON_domain.
DR InterPro; IPR002861; Reeler_dom.
DR InterPro; IPR042307; Reeler_sf.
DR PANTHER; PTHR45828; CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE; 1.
DR PANTHER; PTHR45828:SF3; FERRIC-CHELATE REDUCTASE 1; 1.
DR Pfam; PF03351; DOMON; 1.
DR Pfam; PF02014; Reeler; 1.
DR SMART; SM00665; B561; 1.
DR SMART; SM00664; DoH; 1.
DR PROSITE; PS50939; CYTOCHROME_B561; 1.
DR PROSITE; PS50836; DOMON; 1.
DR PROSITE; PS51019; REELIN; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053858};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..593
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001966860"
FT TRANSMEM 376..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..179
FT /note="Reelin"
FT /evidence="ECO:0000259|PROSITE:PS51019"
FT DOMAIN 216..331
FT /note="DOMON"
FT /evidence="ECO:0000259|PROSITE:PS50836"
FT DOMAIN 336..535
FT /note="Cytochrome b561"
FT /evidence="ECO:0000259|PROSITE:PS50939"
SQ SEQUENCE 593 AA; 66295 MW; 155711A96D6087AC CRC64;
MELPGLAFAV WIFICFYASV DGYPSGKVRE ACTSMIPCHG SSPQLSPEHT ITVNGTEFKP
GDNIEVHLFG PDFEGFFIQA RDAEHLDGPA VGSFMLVDRR LSQLLTCGRT KNSAVSHTSK
AKKKYVKVYW IAPGDAPKRV QFLATVVKKY KTFWVKIPGP IVSQPNVQSP TTPLHATSEV
VSTSHLVSSL SKPFNASGCG STKFCIRNPS NCDPESASCF FLSFQQEKNS VFIEMSGPSE
GYLAFALSYD QWMGGDDAYL CINEDHRVHV STAYLKGRSP PILDSENALE DVSWRLVDGV
LQCSFRRSIR LPTYKGRFNL DASYYIFLAD GETSEGGRIH KHHRQPLITN GIYNVTGLPQ
DIGGSRSPRL IKAHGALMFI AWITTVSIGV IVARFFKPVW SHSFLFGKEM WFQVHRLLML
TTVTITSISF VLPFIYRGGW SQQAGFHPYL GCTVMALTIF QPLMAGFRPS RHAPRRQLFN
WFHWSTGTTA RILAVVTMFL GMDLPALDLP DPWDTYTMIG FVAWHVSIDV LLEIHSYCLV
RKVELIEDDR VQILQSLTSA EAEGRLFKQI VLTIYVCGNI VFLIAFLAAV NQI
//
