ID   A0A0A0AKX4_CHAVO        Unreviewed;       739 AA.
AC   A0A0A0AKX4;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Solute carrier family 12 member 8 {ECO:0000313|EMBL:KGL95149.1};
DE   Flags: Fragment;
GN   ORFNames=N301_09541 {ECO:0000313|EMBL:KGL95149.1};
OS   Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX   NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL95149.1, ECO:0000313|Proteomes:UP000053858};
RN   [1] {ECO:0000313|EMBL:KGL95149.1, ECO:0000313|Proteomes:UP000053858}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL95149.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC12A transporter family.
CC       {ECO:0000256|ARBA:ARBA00010593}.
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DR   EMBL; KL872330; KGL95149.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A0AKX4; -.
DR   STRING; 50402.A0A0A0AKX4; -.
DR   Proteomes; UP000053858; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR004841; AA-permease/SLC12A_dom.
DR   InterPro; IPR004842; SLC12A_fam.
DR   PANTHER; PTHR11827:SF6; SOLUTE CARRIER FAMILY 12 MEMBER 8; 1.
DR   PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR   Pfam; PF00324; AA_permease; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053858};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        52..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        120..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        163..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        248..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        281..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        324..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        374..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        398..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        623..655
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        661..681
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          60..412
FT                   /note="Amino acid permease/ SLC12A"
FT                   /evidence="ECO:0000259|Pfam:PF00324"
FT   REGION          541..591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KGL95149.1"
FT   NON_TER         739
FT                   /evidence="ECO:0000313|EMBL:KGL95149.1"
SQ   SEQUENCE   739 AA;  80869 MW;  77C4DC3F1D00600F CRC64;
     EGGGKAKDTM FSLNGARSEG YVQELFHEEA QQVSQTQSKP WWKIQLFVWE PVLFGTWDGV
     FTSCMINIFG VVLFLRTGWL VGNTGIVMGM FLVSFVILVA LVTVLSGIGV CEKCSIGSGG
     VYSMISTVLG GQVGGTIGLL YIFGQCVAGA MYITGFAESI ADVLSLSNIW AVRGISLAVL
     LGLLGINLAG VKWIIRLQLL LLFLLAVSTL DFVIGSFTHL DPEHGFVGYS EELMFNNTLP
     DYSKGESFFT VFGVFFPAAT GVMAGFNMSG DLQKPAANIP LGSLAAIGTS WFLYMVFVFL
     LGAICTRQSL RYDFMIAEKV SLVGFLFLLG LYISSLASCM GGLYGAPRIL QCIAQENVIP
     MLAFLGRGKG PNKTPVAAIC LTSLITMAFV FIGQVNVLAP IVTINFMLTY IAVDYSYFSV
     SLSYNVQQKL DETQMENSRP AHSSQPLIFN KPSSRVADGV IQSRSNGTLL EFTKDMDQLF
     KPFRSEPGTC KKGAGDLTQK VKQKKAKKPA KQTLQDSFLL DLPHDAPLAQ YGWDVTTEPH
     HKSRQDLAEQ GCQRDTGPCL SPTADAQRTP GLLEPGEQRC SETPVLPGRR GEELPIKQQN
     PELGIQQIPE SFYSKFCNHW ISFVGAIVSL IIMFVIQWIY TLVSLGAAVI LYFYIGQVSP
     GLPLGAAANF SFLGWIKSVL ITSCRRRPSP KEQIVVTPSF ATVGMETTQL TEENADFASR
     DRYHQSSLIS REEFGNQFQ
//