ID A0A0A0AYN1_CHAVO Unreviewed; 1221 AA.
AC A0A0A0AYN1;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Rap guanine nucleotide exchange factor 1 {ECO:0000313|EMBL:KGL99036.1};
DE Flags: Fragment;
GN ORFNames=N301_12420 {ECO:0000313|EMBL:KGL99036.1};
OS Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL99036.1, ECO:0000313|Proteomes:UP000053858};
RN [1] {ECO:0000313|EMBL:KGL99036.1, ECO:0000313|Proteomes:UP000053858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL99036.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL873508; KGL99036.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A0AYN1; -.
DR STRING; 50402.A0A0A0AYN1; -.
DR Proteomes; UP000053858; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF99; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000053858}.
FT DOMAIN 830..954
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 984..1208
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 295..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..250
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL99036.1"
FT NON_TER 1221
FT /evidence="ECO:0000313|EMBL:KGL99036.1"
SQ SEQUENCE 1221 AA; 135893 MW; 725825A94F3DD0B1 CRC64;
DSERSHLSSF TMKLKGKFHS PKIKRTPSKK GKQADLTVKT PEKSANKNVS WLEEKEKEVV
SALRYFKTIV DKMAVDKKVL EMLPGSASKV LEAILPLVQT DPRIQQSSAI SSCYSRVYQS
LANLIRWSDQ VMLEGVNSED KEMVTTVKGV IKAVLDGVKE LVRLTIEKQE HPSPTSPVKP
SLPACKSDSP SELPLTDREM EILNKTTNMT QSNELLTDSM DEEVAPPKPP LPSIRVAENS
PPPALPPKKR QSAPSPTRVA VVAPMSRATS GSSLPVGINR QDFDVDCYAQ RRLSGGSHSY
GGESPRLSPC SSIGKLSKSD EQLSSLDRDS GQCSRNTSCE TLDQSDHYDP DYEFLQQDLS
NADQIPQQMP GILSPLPESL GESGSPFHGH AFQLPQGSAP LLEFCSLSGA AQPTETPPAL
PEKKRRSAAS QTSDNSGCRV SYERHPSQYD NISEDDMQNA ASVPSVPFTP FAAVLPFQQG
NSSAPVEFIA DFAAPDSNSD PEKPPPLPEK KNKHMTAYMQ FVEDYSEPQP SVFYQTPQNE
HIYQQKNKHL MEVYGFNDSF ISLDPSQDLA PPPALPPKQR QLQASYAASS FSSVSYCVQQ
TKVPFTPEDT GATQGLTMSV SNSFLNRHSS FPVHSYKSVF RSYSQDFVPH NQVSIPPFLS
STSSSCSTPP FPPVHPSQSS ALAVPAAASQ SPSTVDVPNS SSQESSFNGN APVCLPSETS
FTDSLQTPSS ENASEEAGEG EYVNLYSSGQ SNGELPRSEG ESPPVKDSHS KDSASNSSAM
GKEGKDGAER QQQSTDTLES SQLEEEVDEL SLIDHSEIMA RLTLKQEGDD GPDVRGGSGD
ILLVHATETD RKDLVLYCEA FLTTYRTFIT PEELIKKLQF ATTYEKFCHF PDTFKKRVSK
NTFFVLVRVV DELCLVELTE EILKLLMDLV FRLVCNGELS LARVLRKNIL DKVDQKKLLS
YANSIKPLAA RGVAARPGTL HDFHSHEIAE QLTLLDAELF YKIEIPEVLL WAKEQNEEKS
PNLTQFTEHF NNMSYWVRSI IMLQEKAQDR ERLLLKFIKI MKHLRKLNNF NSYLAILSAL
DSAPIRRLEW QKQTSEGLAE YCTLIDSSSS FRAYRAALAD VEPPCIPYLG LILQDLTFVH
LGNPDYIDSK VNFSKRWQQF NILDSMRCFQ QVHYDIKRND DIVSFFNDFS DHLAEEALWE
LSLKIKPRNI TRRKTDREEK T
//
