ID   A0A0A0D603_9PROT        Unreviewed;       798 AA.
AC   A0A0A0D603;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:KGM33534.1};
DE   Flags: Fragment;
GN   ORFNames=P409_15320 {ECO:0000313|EMBL:KGM33534.1};
OS   Inquilinus limosus MP06.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Inquilinus.
OX   NCBI_TaxID=1398085 {ECO:0000313|EMBL:KGM33534.1, ECO:0000313|Proteomes:UP000029995};
RN   [1] {ECO:0000313|EMBL:KGM33534.1, ECO:0000313|Proteomes:UP000029995}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MP06 {ECO:0000313|EMBL:KGM33534.1,
RC   ECO:0000313|Proteomes:UP000029995};
RA   Pino M., Di Conza J., Gutkind G.;
RT   "Genome sequence determination for a cystic fibrosis isolate, Inquilinus
RT   limosus.";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGM33534.1}.
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DR   EMBL; JANX01000173; KGM33534.1; -; Genomic_DNA.
DR   RefSeq; WP_034838534.1; NZ_JANX01000173.1.
DR   AlphaFoldDB; A0A0A0D603; -.
DR   OrthoDB; 9772207at2; -.
DR   Proteomes; UP000029995; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          301..377
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KGM33534.1"
SQ   SEQUENCE   798 AA;  88199 MW;  292C1B0E44AD326C CRC64;
     LGEAERAATV AAHNGLAAAL RRLKERFPPQ GRLAITGHAH IDLAWLWPYA ETRRKARRTF
     HTALRLIERF PGFVFNQSTA AYYAQVEADD PDLFAAIRAR AEEGRWEAIG GLWVEPDTNM
     PTGESLVRQA LYGQRYFERT FGRRHSVCWL PDCFGFSPAL PQILRQGGMD SFFTIKVNWS
     ETNRFPHDLF QWEGLDGSRV LAHTFDNPIE GYNGTIRADC VLPTWRNFRG KTMHDESLLA
     VGFGDGGGGV TPEMLERQAQ LADFPALPEL RPARVEEFFG RIRERAAVDE LPVWLGEIYL
     ELHRGTLTSQ GRTKRLNRQA ERALLAAEVA GSLATLLGGP AFASLEPAWR GLLKNQFHDI
     LPGSSIREVY EDAERELTAA RDAGLDRQAE AMAAIAASLP NGGTADALVV VNPDLSPRPL
     RLELEGEAVA PDLTVPPLGV VVLDRAALQP APGLSASWST TGSRLENRFL QVEIGADGTI
     ARLLHKPTGR DALAGRGNQL WLYPADKPRS WDAWDVEADC DRQGFELTGL EDTELVEDGP
     DRAALRLVRR WRDSTITQTL TLWANAPRLD IHTRLDWHDR RVLLRALVPV AVRAETASFE
     CAFGVVRRPT HRNTSWDQAK FEVPGHRFAD LSEPGFGVAL LNDGKYGHSA LGNVLGLSLV
     RAPIYPDPLA DEGVQDFTYA ILPHAGDWHE GGVREAAEDL NQPLLALPAR NLAAGLHTPL
     MVSGIKAALA ALKPAEEGGG LVLRLYEPAG ARGTLSITMP EGWRLGEAVS LLEEPAPRER
     THDLEPFELR SWRLRPER
//