ID A0A0A0DR75_9BURK Unreviewed; 586 AA.
AC A0A0A0DR75;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=3-ketosteroid-delta-1-dehydrogenase {ECO:0000313|EMBL:KGM41151.1};
GN ORFNames=JY96_16765 {ECO:0000313|EMBL:KGM41151.1};
OS Aquabacterium sp. NJ1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Aquabacterium.
OX NCBI_TaxID=1538295 {ECO:0000313|EMBL:KGM41151.1, ECO:0000313|Proteomes:UP000029993};
RN [1] {ECO:0000313|EMBL:KGM41151.1, ECO:0000313|Proteomes:UP000029993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJ1 {ECO:0000313|EMBL:KGM41151.1,
RC ECO:0000313|Proteomes:UP000029993};
RA Masuda H.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KGM41151.1, ECO:0000313|Proteomes:UP000029993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJ1 {ECO:0000313|EMBL:KGM41151.1,
RC ECO:0000313|Proteomes:UP000029993};
RA Shiwa Y., Yoshikawa H., Zylstra G.J.;
RT "The draft genome sequence of a soil bacterium, Aquabacterium sp. strain
RT NJ1, capable of utilizing both liquid and solid n-alkanes.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGM41151.1}.
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DR EMBL; JRKM01000001; KGM41151.1; -; Genomic_DNA.
DR RefSeq; WP_035039237.1; NZ_JRKM01000001.1.
DR AlphaFoldDB; A0A0A0DR75; -.
DR STRING; 1538295.JY96_16765; -.
DR eggNOG; COG1053; Bacteria.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000029993; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000029993};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..586
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001968639"
FT DOMAIN 39..565
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 586 AA; 62623 MW; 27F15AB001BB9A5B CRC64;
MPVSRTRRQV LQGAASAALT TSVMGSLSSP AQAAEDTFDV VVIGSGAAGM TAALSAAKRG
LRVVVIEKAD KFGGSTARSG AGIWIRNNEV LQKAGVTDTP EQAAAYLDAV VGPIVPPERK
ATYLQQGPAM ISFILRNTPL RFRWMEGYSD YYPELPGGKP NGASIEPDQF DGRLLGKELA
NLNPPYLATP PGVVIFGGEY KWLNLAAVSA KGALIAANAV ARYAEAMLKG QIPLTMGQAL
AAGLRAGLLQ ANVPVWLNTP LIDLQFDANG RVNGVLVNKN GNPTVIRATR GVVMAAGGFE
HNLKMRLDYQ QHPITTDWTV GTKTNTGDGI QAGQRAGAAL DLMDDAWWGP VIPLPEGPYF
VLAERTLPGS IMVNSQGQRF VNEAAPYTDF VHATYKQALV SQDVNAWMVV DQRYRNRYLF
KETLPFLPLP QRWYDAGVVV KDLTLEGLAT KMGVPPAALR NTVQRFNGFA DAGKDLDFHR
GDSVYDHYYT DPAVRPSSSL AALRHAPFYA FKIRPGDLGT KGGLRTDARA RVLRDDGSVI
EGLYAAGNNS ASVMGHSYAG AGSTIGPAMT FGYVAGNDLA DQAPSV
//
