ID A0A0A0K1I7_CUCSA Unreviewed; 907 AA.
AC A0A0A0K1I7;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Beta-adaptin-like protein {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=Csa_7G041890 {ECO:0000313|EMBL:KGN43495.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN43495.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN43495.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC -!- FUNCTION: Subunit of clathrin-associated adaptor protein complex that
CC plays a role in protein sorting in the late-Golgi/trans-Golgi network
CC (TGN) and/or endosomes. The AP complexes mediate both the recruitment
CC of clathrin to membranes and the recognition of sorting signals within
CC the cytosolic tails of transmembrane cargo molecules.
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SUBUNIT: Adaptor protein complexes are heterotetramers composed of two
CC large adaptins (beta-type subunit and alpha-type or delta-type or
CC epsilon-type or gamma-type subunit), a medium adaptin (mu-type subunit)
CC and a small adaptin (sigma-type subunit).
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
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DR EMBL; CM002928; KGN43495.1; -; Genomic_DNA.
DR RefSeq; XP_004144506.1; XM_004144458.2.
DR AlphaFoldDB; A0A0A0K1I7; -.
DR STRING; 3659.A0A0A0K1I7; -.
DR EnsemblPlants; KGN43495; KGN43495; Csa_7G041890.
DR GeneID; 101203329; -.
DR Gramene; KGN43495; KGN43495; Csa_7G041890.
DR KEGG; csv:101203329; -.
DR eggNOG; KOG1061; Eukaryota.
DR OMA; NPPEVQW; -.
DR OrthoDB; 648032at2759; -.
DR Proteomes; UP000029981; Chromosome 7.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 2.60.40.1150; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF3; AP COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 672..786
FT /note="Clathrin adaptor alpha/beta/gamma-adaptin appendage
FT Ig-like subdomain"
FT /evidence="ECO:0000259|SMART:SM00809"
FT DOMAIN 795..906
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
FT REGION 593..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 907 AA; 100652 MW; 6D58EFF06F089B85 CRC64;
MSGHDSKYFS TTKKGEIPEL KEELNSQYKD KRKDAVKKVI AAMTVGKDVS SLFTDVVNCM
QTENLELKKL VYLYLINYAK SQPDLAILAV NTFVKDSQDP NPLIRALAVR TMGCIRVDKI
TEYLCDPLQR CLKDDDPYVR KTAAICVAKL FDINAELVED RGFLDSLKDL ISDNNPMVVA
NAVAALAEIQ EDSSKPIFEI TSHTLSKLLT ALNECTEWGQ VFILDALSRY KTEDAREAEN
IVERVTPRLQ HANCAVVLSA VKMILLQMEL ITSTDIVRNL CKKMAPPLVT LLSSEPEIQY
VALRNINLIV LKRPTILAHE IKVFFCKYND PIYVKVEKLE IMIKLASDRN IDQVLLEFKE
YATEVDVDFV RKAVRAIGRC AIKLERAAER CISVLLELIK IKVNYVVQEA IIVIKDIFRR
YPNTYESIIA TLCESLDTLD EPEAKASMIW IIGEYAERID NADELLESFL ESFPEEPAQV
QLQLLTATVK LFLKKPTEGP QQMIQAVLNN ATVETDNPDL RDRAYIYWRL LSTDPEAAKD
VVLAEKPVIG DDSNLLDSTL LDELLANIAT LSSVYHKPPE AFVTRVKTVS QRIDDDDYPE
GSNSGHSEPP ANAASGGGAS PTTSDAPYSV TKRPVPTLAP APSSSPPPAS IPDLLGDLIG
LDNSAIAPVD QSAAPAGSPL PILLTASAGQ GLQISAQLIR HDGQIFYSLT FDNSSQMILD
GFMIQFNKNT FGLAAAGPLQ VPQLQPGSIA NTLLPMVVFQ NMSQGPPSSL LQVAVKNNQQ
PVLYFSDKIL MHIFFTEDGR MERASFLETW RSLPDSNEVI RDLPTILINN VEAIVERLAA
TNMFFIAKRK HANQDVFYFS TKIPRGIPFL IELTTVIGSP GLKCAVKTPN IDMAPLFFEA
LEILLKE
//
