ID   A0A0A0K3H0_9MICO        Unreviewed;       304 AA.
AC   A0A0A0K3H0;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=5'-3' exonuclease {ECO:0000313|EMBL:KGN42857.1};
GN   ORFNames=N801_12000 {ECO:0000313|EMBL:KGN42857.1};
OS   Knoellia aerolata DSM 18566.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC   Knoellia.
OX   NCBI_TaxID=1385519 {ECO:0000313|EMBL:KGN42857.1, ECO:0000313|Proteomes:UP000030013};
RN   [1] {ECO:0000313|EMBL:KGN42857.1, ECO:0000313|Proteomes:UP000030013}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18566 {ECO:0000313|EMBL:KGN42857.1,
RC   ECO:0000313|Proteomes:UP000030013};
RA   Zhu W., Wang G.;
RT   "The genome sequence of Knoellia aerolata.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGN42857.1}.
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DR   EMBL; AVPL01000002; KGN42857.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A0K3H0; -.
DR   STRING; 1385519.N801_12000; -.
DR   eggNOG; COG0258; Bacteria.
DR   Proteomes; UP000030013; Unassembled WGS sequence.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR   CDD; cd09898; H3TH_53EXO; 1.
DR   CDD; cd09859; PIN_53EXO; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR   InterPro; IPR002421; 5-3_exonuclease.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR020045; DNA_polI_H3TH.
DR   InterPro; IPR038969; FEN.
DR   InterPro; IPR008918; HhH2.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR   PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR   Pfam; PF01367; 5_3_exonuc; 1.
DR   Pfam; PF02739; 5_3_exonuc_N; 1.
DR   SMART; SM00475; 53EXOc; 1.
DR   SMART; SM00279; HhH2; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Exonuclease {ECO:0000313|EMBL:KGN42857.1};
KW   Hydrolase {ECO:0000313|EMBL:KGN42857.1};
KW   Nuclease {ECO:0000313|EMBL:KGN42857.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030013}.
FT   DOMAIN          1..272
FT                   /note="5'-3' exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00475"
SQ   SEQUENCE   304 AA;  32784 MW;  620D704DBC5272BC CRC64;
     MLLLDSASLY FRAFFGVPDQ RDSADEHPTN ALRGFLDMIA TLVNAHRPTH LVACWDDDWR
     PQFRVDLIPT YKTHRLTEGS DVVEESPDDL TPQVPLIRDA LAALGIPRLG APGFEADDVI
     GTLVERHRGS MAIDVVTGDR DLLQLIDDAH RVRVLYTGKG GVREPDIGTQ AYLQEKYAVP
     DGDAYADMSI LRGDTSDGLP GVKGIGYKTA AQLIAAYGSL AGLRKAVADG DPAIKGARRT
     HLEAASAYLD VAPRVVRVAR DAPVADVDIT LPTAVADTRL LSELASTYGV TNPINRVLAA
     LQIP
//