ID A0A0A0KAK5_CUCSA Unreviewed; 716 AA.
AC A0A0A0KAK5;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
GN ORFNames=Csa_7G447790 {ECO:0000313|EMBL:KGN45417.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN45417.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN45417.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC -!- SUBCELLULAR LOCATION: Cell projection, podosome
CC {ECO:0000256|ARBA:ARBA00004188}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CM002928; KGN45417.1; -; Genomic_DNA.
DR RefSeq; XP_004141829.1; XM_004141781.2.
DR AlphaFoldDB; A0A0A0KAK5; -.
DR STRING; 3659.A0A0A0KAK5; -.
DR EnsemblPlants; KGN45417; KGN45417; Csa_7G447790.
DR GeneID; 101215447; -.
DR Gramene; KGN45417; KGN45417; Csa_7G447790.
DR KEGG; csv:101215447; -.
DR eggNOG; KOG2190; Eukaryota.
DR OMA; QTHAAQC; -.
DR OrthoDB; 384756at2759; -.
DR Proteomes; UP000029981; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR CDD; cd22459; KH-I_PEPPER_rpt1_like; 1.
DR CDD; cd22460; KH-I_PEPPER_rpt2_like; 2.
DR Gene3D; 3.30.310.210; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288:SF344; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; 1.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 4.
DR SMART; SM00322; KH; 4.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 4.
DR PROSITE; PS50084; KH_TYPE_1; 4.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 197..272
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 342..417
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 425..500
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 640..710
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 534..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..42
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 302..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 716 AA; 77328 MW; F027BBAAFDA6A4D3 CRC64;
MDTNFSPKRP PDAISDPSLS AGRSVRPRQL PPPPPLPPPV STTAPATLGL DTTTRDAPVL
KPSSPSDTLF RLLCPASKVS SILRHLRDIP GARIHVDEPL PSCEECVLVI LAGSPSKPAH
TNPGNDREFR EHDVHRNVSS DTVAGDSDER SQAQQALLRT FESIVRMNED SGENQEIQKK
NADSAPNDRI SGGETDGLVV CRLLAPSHQV GRVLGRGGKT VEKIRQESMA HVKIFPKDQN
PACASPQDEL IQISGNFSAV MKALSSVSSC LQDSPRVDSS NSSSTKSLGP TSHASSMSVQ
DEEPSPRRRY GSHHNADYRS RSYSSIPGHE NAGAGPRAAM EEDVVFRLLC QPDKVGSLIG
KGGTVVRALQ NETGASIKIV DTPDLDERLV VISARETLEQ TYSPAQEAVI RAHCRIAEIG
YEPGAAVVAR LLVHGQQIGY LVGRGGHIIN DMRRGTGTSI QIFPRDQIQN GGPMSDEVVQ
VIGNLPSVQD ALFHITNRIR DTFFPMRPHV PNFNNHPPYL SPHPETPPPL FRPGSNAHSP
GYYPSQAGGL RGTERPPYHS HPLDHQPAYP HNVSFGGGNN MDGVPYPHGM ERPGPGSFER
PSPRSWTSQV SSEIPKGPTD GFGMVSRNEP YGSGGPHFMG GTSMEMVIPQ TLICHIYGEN
NNNIAHVQQI SGAMLVVHDA KPGMFDGKVI MSGTPDQIRA AQRLVHAFIL CGKTQS
//
