ID A0A0A0KLG5_CUCSA Unreviewed; 490 AA.
AC A0A0A0KLG5;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN ORFNames=Csa_6G517300 {ECO:0000313|EMBL:KGN49222.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN49222.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN49222.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC -!- SIMILARITY: Belongs to the glutaredoxin family. CGFS subfamily.
CC {ECO:0000256|ARBA:ARBA00008983}.
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DR EMBL; CM002927; KGN49222.1; -; Genomic_DNA.
DR RefSeq; XP_004134708.1; XM_004134660.2.
DR AlphaFoldDB; A0A0A0KLG5; -.
DR SMR; A0A0A0KLG5; -.
DR STRING; 3659.A0A0A0KLG5; -.
DR EnsemblPlants; KGN49222; KGN49222; Csa_6G517300.
DR GeneID; 101205781; -.
DR Gramene; KGN49222; KGN49222; Csa_6G517300.
DR KEGG; csv:101205781; -.
DR eggNOG; KOG0911; Eukaryota.
DR OMA; HDIVMEL; -.
DR OrthoDB; 1038at2759; -.
DR Proteomes; UP000029981; Chromosome 6.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006879; P:intracellular iron ion homeostasis; IBA:GO_Central.
DR CDD; cd03028; GRX_PICOT_like; 3.
DR CDD; cd02984; TRX_PICOT; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 4.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR033658; GRX_PICOT-like.
DR InterPro; IPR004480; Monothiol_GRX-rel.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR NCBIfam; TIGR00365; Grx4 family monothiol glutaredoxin; 3.
DR PANTHER; PTHR10293; GLUTAREDOXIN FAMILY MEMBER; 1.
DR PANTHER; PTHR10293:SF73; GLUTAREDOXIN-3; 1.
DR Pfam; PF00462; Glutaredoxin; 3.
DR Pfam; PF00085; Thioredoxin; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 4.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 3.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981}.
FT DOMAIN 1..107
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 490 AA; 53798 MW; CDA474C0A8EC718F CRC64;
MSGSVKDVKS KAELDALLRS DALVILHFWA SWCDASNHMD QVFSHLATDF PHAHFLRVEA
EEQPEISEAY SVAAVPYFVF IKDGKTVDTL EGADPSSLAN KVAKASGAIN TGEPAAPASL
GMAAGPAILE TVRELARDNG SVTESKVQPG LSSALQTKIQ QLIDSNSVML FMKGSPEEPR
CGFSRKVVDI LKEENVKFGS FDILSDNEIR EGLKKFSNWP TFPQLYCKGD LLGGSDIAIA
MHESGELKEV FRDHGIENIV SDEVKTAKPD RKGGISENSG LSEALASRLK TLINSSPVML
FMKGKPDEPK CGFSHKVVEI LREENVNFET FDILSDDEVR QGIKDYSNWS SFPQLYIKGE
LVGGSDIVLQ MQRSGELRKV LENKGIIKKD TIEDRLKKLT TSSPVMLFMK GIPDAPKCGF
SSKVVNALKE EGIDFGSFDI LSDEEVRQGL KVYSNWPTFP QLYYKGDLIG GCDIVLELKS
NGELKATLSE
//
