ID A0A0A0KP31_CUCSA Unreviewed; 695 AA.
AC A0A0A0KP31;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Geranylgeranyl transferase type-2 subunit alpha {ECO:0000256|RuleBase:RU367120};
DE EC=2.5.1.60 {ECO:0000256|RuleBase:RU367120};
DE AltName: Full=Geranylgeranyl transferase type II subunit alpha {ECO:0000256|RuleBase:RU367120};
GN ORFNames=Csa_6G525330 {ECO:0000313|EMBL:KGN49446.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN49446.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN49446.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC -!- FUNCTION: Catalyzes the transfer of a geranyl-geranyl moiety from
CC geranyl-geranyl pyrophosphate to cysteines occuring in specific C-
CC terminal amino acid sequences. {ECO:0000256|RuleBase:RU367120}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=geranylgeranyl diphosphate + L-cysteinyl-[protein] =
CC diphosphate + S-geranylgeranyl-L-cysteinyl-[protein];
CC Xref=Rhea:RHEA:21240, Rhea:RHEA-COMP:10131, Rhea:RHEA-COMP:11537,
CC ChEBI:CHEBI:29950, ChEBI:CHEBI:33019, ChEBI:CHEBI:57533,
CC ChEBI:CHEBI:86021; EC=2.5.1.60;
CC Evidence={ECO:0000256|ARBA:ARBA00001577,
CC ECO:0000256|RuleBase:RU367120};
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC family. {ECO:0000256|ARBA:ARBA00006734, ECO:0000256|RuleBase:RU367120}.
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DR EMBL; CM002927; KGN49446.1; -; Genomic_DNA.
DR RefSeq; XP_004134583.1; XM_004134535.2.
DR AlphaFoldDB; A0A0A0KP31; -.
DR STRING; 3659.A0A0A0KP31; -.
DR EnsemblPlants; KGN49446; KGN49446; Csa_6G525330.
DR GeneID; 101216457; -.
DR Gramene; KGN49446; KGN49446; Csa_6G525330.
DR KEGG; csv:101216457; -.
DR eggNOG; KOG0529; Eukaryota.
DR OMA; YNEIGSH; -.
DR OrthoDB; 5489560at2759; -.
DR Proteomes; UP000029981; Chromosome 6.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005968; C:Rab-protein geranylgeranyltransferase complex; IBA:GO_Central.
DR GO; GO:0004663; F:Rab geranylgeranyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0097354; P:prenylation; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.120; Protein prenylyltransferase; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002088; Prenyl_trans_a.
DR PANTHER; PTHR11129:SF2; GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11129; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT; 1.
DR Pfam; PF13516; LRR_6; 1.
DR Pfam; PF01239; PPTA; 5.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR PROSITE; PS51450; LRR; 2.
DR PROSITE; PS51147; PFTA; 5.
PE 3: Inferred from homology;
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602,
KW ECO:0000256|RuleBase:RU367120};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|RuleBase:RU367120}.
SQ SEQUENCE 695 AA; 79433 MW; 89EEF1E99129417A CRC64;
MHGRPRKPQK PEEAEASAVE AAKLQNLQSQ LLANHHQKNY AKEALEVSAN LLEMNPDLYT
AWNYRKLAVE HYLKESSSDI VSIEAILNEE LRVAESALRQ NVKSYGAWYH RKYILSKGHS
STDHELRLLG KFQKLDARNF HAWNYRRFVA GLMNIPEDKE LKYTTDMIDT NFSNYSAWHN
RSALLAKLLN QKAEGYFPME KVLNEEYELV HQAIFTDPDD QSGWFYHLWL LDQTVKANPP
YLVSSWPPHS FNVALSRTRC LDNHTPSPFC SFYSDSGTIP LILYFDQPVQ GVDSSSVIVK
STANLRDLIW KPLSKCNRDT SKAWISHLTF PQEELNSEFY SVEVSIGHSQ KIASATGFHH
VKPTQISFKV AVNFKETPSE DFGNERIRWK DENFTSCGIS PHNFPFGSDN STSEGDYAPS
TSEWCVETIN NEIALFRELL SETDCKIGKL TLARLLMAHA ATSPHANEMI QLEEVLDLYQ
DLMKFDPSHF HFYKDEHSLV LLQKVTSTRE SLLRHCYSYK EQTSPYIDST ACLRLNNLSI
SRIGCVEKIL WVQLLDLSHN ELGSIDGLES MQLLSCLSLS NNKIGSFTAL EPLRLLKSLK
VLDISYNEIG SHSIDTTRYL FSSPLSHSEE IDLSSDEMAT NCTDLASYWE AYFLFKDISL
MQLDIEGNTI SSESFKAFLV KILPKLHWLD GKQVQ
//
