ID A0A0A0KYM5_CUCSA Unreviewed; 756 AA.
AC A0A0A0KYM5;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Apyrase 7 {ECO:0008006|Google:ProtNLM};
GN ORFNames=Csa_4G056630 {ECO:0000313|EMBL:KGN53472.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN53472.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN53472.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283}.
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DR EMBL; CM002925; KGN53472.1; -; Genomic_DNA.
DR RefSeq; XP_004147770.1; XM_004147722.2.
DR AlphaFoldDB; A0A0A0KYM5; -.
DR STRING; 3659.A0A0A0KYM5; -.
DR EnsemblPlants; KGN53472; KGN53472; Csa_4G056630.
DR GeneID; 101219987; -.
DR Gramene; KGN53472; KGN53472; Csa_4G056630.
DR KEGG; csv:101219987; -.
DR eggNOG; KOG1386; Eukaryota.
DR OMA; PEYYVIL; -.
DR OrthoDB; 1222189at2759; -.
DR Proteomes; UP000029981; Chromosome 4.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IBA:GO_Central.
DR GO; GO:0009134; P:nucleoside diphosphate catabolic process; IBA:GO_Central.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF125; APYRASE 7-RELATED; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 120..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 591..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 726..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..756
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 292
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 323..327
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 756 AA; 84595 MW; 10816A792FBE041C CRC64;
MVFGKFRDIL SSVATRLSGR HSSTDAFKSS SSPPLIASPS PLVAGFVSPA LKNNLRLSSS
LQDLSTYRRL DLEEGNRGVE NASPDFSPLQ RENASSSFSK EKTLPGSSFW WLTRKWMRTV
VLFLCLLLFC FLIYTVSMYI YSYWSQGTPR YYVVLDCGST GTRAFVYQAN VNYKKNGALP
IAIRSYTGQK KKLKSQSGRA YDRMETEPGL DKLVRNMTGL KKAIKPLLQW AEKQIPKRAH
ESTSLFLYAT AGVRKLPPAD SKWLLDSAWS ILKSSRFLCQ REWVKTISGT EEAYYGWIAL
NYQKELLGAT PREPTYGALD LGGSSLQVTF ESKEQNESSL NIKIGNVDYH LNAYSLTGYG
LNDAFGKSVV HLLRRIQEPE KLDLSNGKFK LNHPCLHSGY NEQYTCNQCG KLLDGGSKSG
ISLRLIGAPN WEECSALAKV AVNFSEWSNT STGVDCDVQP CAITNNYPPP YGNFYAISGF
FVVFRFFNLT SEATLDDVLE RGHKFCEKPW DDAQASVPPQ PFIEQYCFRA PYIVSLLREG
LHITDKQITI GSGSTTWTLG VSLLEAGKAF TVATRLELRG YEIFKMKIDP LILMVVLFTS
LFFLLALSCV RSALPRFFRR PYLPIFRHNA VSTTSVLNIP SPFRLQRWSP MSAGDGRVKM
PLSPTVQGSQ ERPFGLGHGF SSSSGIQLME SSLHRSTSSG VSHSYSSNSL GQMQFDNSSV
GSFWTPRRSQ MRLQSRRSQS REDLSSTLSE THMVKV
//
