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Database: UniProt
Entry: A0A0A0LGF8_CUCSA
LinkDB: A0A0A0LGF8_CUCSA
Original site: A0A0A0LGF8_CUCSA 
ID   A0A0A0LGF8_CUCSA        Unreviewed;       320 AA.
AC   A0A0A0LGF8;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-OCT-2019, entry version 27.
DE   RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273};
DE            EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};
GN   ORFNames=Csa_2G031170 {ECO:0000313|EMBL:KGN60958.1};
OS   Cucumis sativus (Cucumber).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae;
OC   Benincaseae; Cucumis.
OX   NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN60958.1, ECO:0000313|Proteomes:UP000029981};
RN   [1] {ECO:0000313|EMBL:KGN60958.1, ECO:0000313|Proteomes:UP000029981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=19881527; DOI=10.1038/ng.475;
RA   Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA   Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA   Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J.,
RA   Jia Z., Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q.,
RA   Li B., Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y.,
RA   Zhao B., Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K.,
RA   Kim J.Y., Xu Y., Heller-Uszynska K., Miao H., Cheng Z., Zhang S.,
RA   Wu J., Yang Y., Kang H., Li M., Liang H., Ren X., Shi Z., Wen M.,
RA   Jian M., Yang H., Zhang G., Yang Z., Chen R., Liu S., Li J., Ma L.,
RA   Liu H., Zhou Y., Zhao J., Fang X., Li G., Fang L., Li Y., Liu D.,
RA   Zheng H., Zhang Y., Qin N., Li Z., Yang G., Yang S., Bolund L.,
RA   Kristiansen K., Zheng H., Li S., Zhang X., Yang H., Wang J., Sun R.,
RA   Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT   "The genome of the cucumber, Cucumis sativus L.";
RL   Nat. Genet. 41:1275-1281(2009).
RN   [2] {ECO:0000313|EMBL:KGN60958.1, ECO:0000313|Proteomes:UP000029981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=19495411; DOI=10.1371/journal.pone.0005795;
RA   Ren Y., Zhang Z., Liu J., Staub J.E., Han Y., Cheng Z., Li X., Lu J.,
RA   Miao H., Kang H., Xie B., Gu X., Wang X., Du Y., Jin W., Huang S.;
RT   "An integrated genetic and cytogenetic map of the cucumber genome.";
RL   PLoS ONE 4:E5795-E5795(2009).
RN   [3] {ECO:0000313|EMBL:KGN60958.1, ECO:0000313|Proteomes:UP000029981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20565788; DOI=10.1186/1471-2164-11-384;
RA   Guo S., Zheng Y., Joung J.G., Liu S., Zhang Z., Crasta O.R.,
RA   Sobral B.W., Xu Y., Huang S., Fei Z.;
RT   "Transcriptome sequencing and comparative analysis of cucumber flowers
RT   with different sex types.";
RL   BMC Genomics 11:384-384(2010).
RN   [4] {ECO:0000313|EMBL:KGN60958.1, ECO:0000313|Proteomes:UP000029981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22047402; DOI=10.1186/1471-2164-12-540;
RA   Li Z., Zhang Z., Yan P., Huang S., Fei Z., Lin K.;
RT   "RNA-Seq improves annotation of protein-coding genes in the cucumber
RT   genome.";
RL   BMC Genomics 12:540-540(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:83421; EC=3.1.3.16;
CC         Evidence={ECO:0000256|SAAS:SAAS01116782};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-
CC         [protein] + phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-
CC         COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:30013, ChEBI:CHEBI:43474, ChEBI:CHEBI:61977;
CC         EC=3.1.3.16; Evidence={ECO:0000256|RuleBase:RU004273,
CC         ECO:0000256|SAAS:SAAS01116780};
CC   -!- SIMILARITY: Belongs to the PPP phosphatase family.
CC       {ECO:0000256|RuleBase:RU004273, ECO:0000256|SAAS:SAAS01017257}.
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DR   EMBL; CM002923; KGN60958.1; -; Genomic_DNA.
DR   RefSeq; XP_011648841.1; XM_011650539.1.
DR   RefSeq; XP_011648842.1; XM_011650540.1.
DR   STRING; 3659.XP_004158736.1; -.
DR   EnsemblPlants; KGN60958; KGN60958; Csa_2G031170.
DR   GeneID; 101211101; -.
DR   Gramene; KGN60958; KGN60958; Csa_2G031170.
DR   KEGG; csv:101211101; -.
DR   KO; K06269; -.
DR   OMA; HESESIC; -.
DR   Proteomes; UP000029981; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR   InterPro; IPR031675; STPPase_N.
DR   Pfam; PF00149; Metallophos; 1.
DR   Pfam; PF16891; STPPase_N; 1.
DR   PRINTS; PR00114; STPHPHTASE.
DR   SMART; SM00156; PP2Ac; 1.
DR   PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000029981};
KW   Hydrolase {ECO:0000256|RuleBase:RU004273,
KW   ECO:0000256|SAAS:SAAS01017252};
KW   Manganese {ECO:0000256|SAAS:SAAS01017251};
KW   Metal-binding {ECO:0000256|SAAS:SAAS01017255};
KW   Protein phosphatase {ECO:0000256|SAAS:SAAS01017274};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029981}.
FT   DOMAIN      121    126       SER_THR_PHOSPHATASE.
FT                                {ECO:0000259|PROSITE:PS00125}.
SQ   SEQUENCE   320 AA;  35999 MW;  E663E0B694064119 CRC64;
     MMTMEGIEKG VLDDIIRRLL EGRGGKQVQL SEAEIRHLCV NAKHIFLSQP NLLRLSAPIR
     ICGDIHGQYK DLLRLFEYGG YPPSANYLFL GDYVDRGKQS LETICLLLAY KIRHPNKVFL
     LRGNHEDAKI NRIYGFYDEC KRRFNVRLWK IFTDCFNCMP VAGLIDDKIL CMHGGISPDL
     KSLDQITQLP RPTEIPDNGL LCDLLWSDPD PSIQGWADSD RGVSCTFGPD RVADFLDKND
     LDLICRGHQV VEDGYEFFAK RRLVTIFSAP NYGGEFDNAG ALLSVDESLV CSFEILKPEQ
     IASGSSSGVI LKKPPKIGRS
//
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