ID A0A0A0LPC4_CUCSA Unreviewed; 681 AA.
AC A0A0A0LPC4;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN ORFNames=Csa_2G249860 {ECO:0000313|EMBL:KGN61831.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN61831.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN61831.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/BELL homeobox family.
CC {ECO:0000256|ARBA:ARBA00006454}.
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DR EMBL; CM002923; KGN61831.1; -; Genomic_DNA.
DR RefSeq; XP_011649247.1; XM_011650945.1.
DR RefSeq; XP_011649248.1; XM_011650946.1.
DR AlphaFoldDB; A0A0A0LPC4; -.
DR STRING; 3659.A0A0A0LPC4; -.
DR EnsemblPlants; KGN61831; KGN61831; Csa_2G249860.
DR GeneID; 101205137; -.
DR Gramene; KGN61831; KGN61831; Csa_2G249860.
DR KEGG; csv:101205137; -.
DR eggNOG; KOG0773; Eukaryota.
DR OMA; GNQQHRF; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000029981; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR006563; POX_dom.
DR PANTHER; PTHR11850:SF386; BEL1-LIKE HOMEODOMAIN PROTEIN 7; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF07526; POX; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00574; POX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000029981}.
FT DOMAIN 403..466
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 405..467
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 150..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..510
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 74908 MW; 8BF3F5B70D6C5961 CRC64;
MATYFSSSNN ERDTTPILYS RGSLLGSYEE TTILPRNMMM HVNSGTYMDS LPSQAQNGCG
QITSVGAAGT TQQQQEFLSN LGGSQIAEHD FNTWREDRSE MLGANSMRGP TNVLHGGQNL
QGQGLSLTLS TQIPSAIQIP SIPYRNSDMG LTSFLSPNPT NSGEDGCRNG ASRDEQLRNG
ENLPPNFQEL AKGEISQYSM STIARTMPNS KYLKAAQQLL DEVVNVRKAL KRPNNDRNQS
SHEHETRSAK NGDTGTKNDS SMLTASGTSS NPQETGSNST CELSHAEKQD LQNKLTKLLY
MLDEVDRRYN QYYHQMQIVV SSFDVIAGCG ASKPYTALAL QTISRHFRCL RDAIAGQVRA
TRKSLGEHEN SGSDKGVGIT RLRYVDQQLR QQRALQQLGM IQQHAWRPQR GLPENSVSIL
RAWLFEHFLH PYPKDSDKIM LARQTGLTRS QVSNWFINAR VRLWKPMVEE MYKEEIGSVD
MDSISSSENA GKATKGDNKT FDDDKEEDLQ QSASSTATER CSAGDIIDLK SDQVSNLGNS
CSNRVASFQN GAHIEARNEL AKPNDELRPN VNNSSFFPDA IVHSQGESDR FMAAAAAYHM
SELGRFGTVG GVSLTLGLQH CEGGGLPLPA GTHHGFAAMR GDDMYNAAAS SLGETVHFEC
VNSGNPQPRF GPSHLYHDFV V
//
