ID A0A0A0LZ21_CUCSA Unreviewed; 976 AA.
AC A0A0A0LZ21;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Lysosomal beta A mannosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=Csa_1G570070 {ECO:0000313|EMBL:KGN66082.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN66082.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN66082.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; CM002922; KGN66082.1; -; Genomic_DNA.
DR RefSeq; XP_011659895.1; XM_011661593.1.
DR AlphaFoldDB; A0A0A0LZ21; -.
DR STRING; 3659.A0A0A0LZ21; -.
DR EnsemblPlants; KGN66082; KGN66082; Csa_1G570070.
DR GeneID; 101207955; -.
DR Gramene; KGN66082; KGN66082; Csa_1G570070.
DR eggNOG; KOG2230; Eukaryota.
DR OMA; AWPNLHW; -.
DR OrthoDB; 2504097at2759; -.
DR Proteomes; UP000029981; Chromosome 1.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR043534; EBDG/EBM.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041351; Ig_GlcNase.
DR PANTHER; PTHR43536; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43536:SF1; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF18368; Ig_GlcNase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981}.
FT DOMAIN 212..331
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 345..470
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 903..968
FT /note="Exo-beta-D-glucosaminidase Ig-fold"
FT /evidence="ECO:0000259|Pfam:PF18368"
SQ SEQUENCE 976 AA; 111083 MW; 21A7A874D9865D3C CRC64;
MAEIGNKVKL NAGWLAARST EVNLTGTQLT TTHPPSITPS SPWMEASVPG TVLGTLVKNK
VVPDPFYGLA NETIIDIADS GREYYTFWFF TTFQCKLQSE SQHLDLNFRA INYSAEVYIN
GHKKVLPKGM FRRHSLDVSE VLHTDGKNLL AVLVHPPDHP GRIPDKGGQG GDHEIGKDVA
AQYVEGWDWM TPIRDRNTGI WDEVSISRTG PVKIIDPHLV STFFDDYKRV YLHATIEIQN
RSSWVSDCSV KIQVTAELEG NICLVEHLQA QKVSVPTGSI IQYTFPQLYF YKPNLWWPNG
MGKQYLYNVV ISIDVDGFGE SDSWSHDFGF RKIESDIDPA TGGRLFKVNG QRIFIRGGNW
ILSDGLLRLS EKRYHTDIKF HADMNFNMIR CWGGGLAERP EFYHYCDIYG LLVWQEFWIT
GDVDGRGDPK SNPDGPLDHD LFLLCARDTV KLLRNHPSLA LWVGGNEQVP PPDINDALKS
DLKLHPHFQP SENNQLMSVL SLTAEDPSEY LDGTRIYIQG SMWDGFANGK GDFSDGPYEI
QYPENFFKDN FYNYGFNPEV GSVGMPVAAT IRATMPPEGW RIPLFKKLPS GYIEEVPNPI
WDYHKYIPYS KPCHVQSQIE LYGSPKDLDD FCLKAQLANY IQYRALIEGW NSRMWKKYTG
FLIWKTQNPW TGLRGQFYDH LLDQTAGFFG CRCAAEPIHV QLNLCTYFIE VVNTTSNEIS
GVAIEASVWD LEGMCPYFKV FEKLSLPPKQ TSSIAEMEYP TYKNSKPVYF LLLKLYKVSN
DGIISRNFYW LHQFGGDYKK LEPYRKINIP IQVTSKVNIK GSSYEVRMNV QNNSKNAESS
RLTYKNNFIN RQDLGDLDSN SLLLENKEQT NEKCSTSFFS KIWRRGSIEN NSSRLVETNG
NDVGVAFFLH FEVHDSKAEE NEEGDTRILP VHYSDNYFSL VPGEAMSINL SFEAPPGVTP
KITLHGWNLS QSFTVC
//
