ID A0A0A0MRK5_HUMAN Unreviewed; 67 AA.
AC A0A0A0MRK5;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Centromere protein W {ECO:0000313|Ensembl:ENSP00000357309.1};
GN Name=CENPW {ECO:0000313|Ensembl:ENSP00000357309.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000357309.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000357309.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=14574404; DOI=10.1038/nature02055;
RA Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R.,
RA Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D.,
RA Andrews T.D., Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J.,
RA Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H.,
RA Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J.,
RA Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E.,
RA Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J.,
RA French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J.,
RA Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C.,
RA Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A.,
RA Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R.,
RA Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M.,
RA Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K.,
RA Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R.,
RA Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A.,
RA Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L.,
RA Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I.,
RA Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y.,
RA Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E.,
RA Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A.,
RA Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W.,
RA Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M.,
RA West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J.,
RA Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M.,
RA Bentley D.R., Coulson A., Durbin R., Hubbard T., Sulston J.E., Dunham I.,
RA Rogers J., Beck S.;
RT "The DNA sequence and analysis of human chromosome 6.";
RL Nature 425:805-811(2003).
RN [2] {ECO:0000313|Ensembl:ENSP00000357309.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC020559; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001273454.1; NM_001286525.1.
DR RefSeq; XP_016866334.1; XM_017010845.1.
DR AlphaFoldDB; A0A0A0MRK5; -.
DR SMR; A0A0A0MRK5; -.
DR MassIVE; A0A0A0MRK5; -.
DR MaxQB; A0A0A0MRK5; -.
DR PaxDb; 9606-ENSP00000357308; -.
DR PeptideAtlas; A0A0A0MRK5; -.
DR Antibodypedia; 32744; 84 antibodies from 23 providers.
DR DNASU; 387103; -.
DR Ensembl; ENST00000368326.5; ENSP00000357309.1; ENSG00000203760.9.
DR GeneID; 387103; -.
DR UCSC; uc032xlg.2; human.
DR CTD; 387103; -.
DR HGNC; HGNC:21488; CENPW.
DR VEuPathDB; HostDB:ENSG00000203760; -.
DR eggNOG; ENOG502SGDW; Eukaryota.
DR GeneTree; ENSGT00390000010369; -.
DR HOGENOM; CLU_2811680_0_0_1; -.
DR OrthoDB; 4220507at2759; -.
DR BioGRID-ORCS; 387103; 812 hits in 1172 CRISPR screens.
DR ChiTaRS; CENPW; human.
DR GenomeRNAi; 387103; -.
DR Proteomes; UP000005640; Chromosome 6.
DR Bgee; ENSG00000203760; Expressed in oocyte and 150 other cell types or tissues.
DR ExpressionAtlas; A0A0A0MRK5; baseline and differential.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0051382; P:kinetochore assembly; IEA:InterPro.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:InterPro.
DR InterPro; IPR028847; CENP-W.
DR Pfam; PF15510; CENP-W; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
SQ SEQUENCE 67 AA; 7894 MW; F2EBD2006700065F CRC64;
MALSTIVSQR KQIKRKAPRG FLKRVFKRKK PQLRLEKSGD LLKSPGQTLV RVNVESLTRS
MYWPQQR
//
