ID A0A0A1CUL1_9MICC Unreviewed; 366 AA.
AC A0A0A1CUL1;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=NAD/mycothiol-dependent formaldehyde dehydrogenase {ECO:0000313|EMBL:AIY00603.1};
GN ORFNames=ART_1004 {ECO:0000313|EMBL:AIY00603.1};
OS Arthrobacter sp. PAMC 25486.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1494608 {ECO:0000313|EMBL:AIY00603.1, ECO:0000313|Proteomes:UP000030301};
RN [1] {ECO:0000313|EMBL:AIY00603.1, ECO:0000313|Proteomes:UP000030301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC25486 {ECO:0000313|EMBL:AIY00603.1,
RC ECO:0000313|Proteomes:UP000030301};
RA Jung J.-H., Joe M.-H., Cho Y.-J., Lee S.G., Han S.J., Lim S., Choi J.-I.;
RT "Complete genome sequence of Arthrobacter sp. PAMC25486 isolated from the
RT Arctic.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP007595; AIY00603.1; -; Genomic_DNA.
DR RefSeq; WP_038462794.1; NZ_CP007595.1.
DR AlphaFoldDB; A0A0A1CUL1; -.
DR STRING; 1494608.ART_1004; -.
DR KEGG; arm:ART_1004; -.
DR HOGENOM; CLU_026673_14_1_11; -.
DR OrthoDB; 334894at2; -.
DR Proteomes; UP000030301; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR017816; MycoS_dep_FDH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR03451; mycoS_dep_FDH; 1.
DR PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43880:SF12; ALCOHOL DEHYDROGENASE CLASS-3; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000030301};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 33..149
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 194..326
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 366 AA; 37503 MW; DEF661FFE4ADCA18 CRC64;
MVNKTVHKVK GAVVLAKDAP VTLETVLVPD PGPGEVLVDI LTSGVCHTDL HYKQGGISDD
FPFLLGHEAT GVVNTVGAGV TNVVPGDRVI LNWRAVCGNC RACAKGQAQY CFNTANATQK
MTLEDGTVLS PALGIGAFIE KTLVAAGQCT KVDADVDPAA VGLLGCGIMA GLGAAINTGG
VKRGDTVAVI GCGGVGAAAI AGAALAGATT VIAVDRDPKK LAAAVALGAT HTVNASQEDA
VVAIQNHTGG FGADVVIDAV GRPETYKQAF YARDLAGTVV LVGVPTPEMT LELPLLDVFG
RGGSLKSSWY GDCLPSRDFP MLVELYKQGK LDLDAFVSER ITINDIEAAF TKMGEGSVLR
SVVEFA
//
