ID A0A0A1CX93_9MICC Unreviewed; 845 AA.
AC A0A0A1CX93;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ART_2196 {ECO:0000313|EMBL:AIY01795.1};
OS Arthrobacter sp. PAMC 25486.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1494608 {ECO:0000313|EMBL:AIY01795.1, ECO:0000313|Proteomes:UP000030301};
RN [1] {ECO:0000313|EMBL:AIY01795.1, ECO:0000313|Proteomes:UP000030301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC25486 {ECO:0000313|EMBL:AIY01795.1,
RC ECO:0000313|Proteomes:UP000030301};
RA Jung J.-H., Joe M.-H., Cho Y.-J., Lee S.G., Han S.J., Lim S., Choi J.-I.;
RT "Complete genome sequence of Arthrobacter sp. PAMC25486 isolated from the
RT Arctic.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP007595; AIY01795.1; -; Genomic_DNA.
DR RefSeq; WP_038464807.1; NZ_CP007595.1.
DR AlphaFoldDB; A0A0A1CX93; -.
DR STRING; 1494608.ART_2196; -.
DR KEGG; arm:ART_2196; -.
DR HOGENOM; CLU_000445_113_1_11; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000030301; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ion channel {ECO:0000313|EMBL:AIY01795.1};
KW Ion transport {ECO:0000313|EMBL:AIY01795.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AIY01795.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000030301};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AIY01795.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:AIY01795.1};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 377..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 615..838
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 845 AA; 89600 MW; 0860D1CAA5C47919 CRC64;
MTRGILRIFL GSAPGVGKTY SMLEEGHAQA AAGVDVVAGV ILDHGRAQTR AQLAGLESVP
TQHLSYRGSD FQELDVAALL ARRPALALVD EYAHSNIPGA GNAKRWQDVE ELLAAGIDVY
STVNVQHLAS LRDVVESITG VRQQETIPDD VVRRAEQIEL VDIPPELLRQ RLSTGHVYAA
DKVDAALANY FRLGNLTALR ELALLWLADR VEEGVAAYRH SHGIAENWPT RERVVVGLSG
GAEGEVLLRR AARILSRVSG GELLAVHVPR SDGVSGDAPS ALEGQRQLVT DLGGSYHSVG
GEDPARALLD FARNAGATQI VIGSSRRKPR LGFLLGAGVG ARVVRDAGDM DVHMVPHPHS
AAGGVVRNRG ELNRKRVVAG FALAVVLPVL VQLGTGPLSL QTTMVIQLAA AIGVALVGGL
WPAILAAVWG SLLLNYFSAP PVGNLTINDP ENLLALLVFL VVAVAVALAV DQSARRSREA
VQAGAEAATL SELARGILAS QDTVQVFLEQ VRDHFGMRSV ALFATAAPPG TWHLAASVGE
EPPQNPAAAD TVEEVSDHWV LGLSGRILPA RDRRLLSAFG AHLLALEQRE ALSETQRENV
QLSQDNNIRT SVLRAVSHDL RTPLAGIKLA VSSLRQTEVT FSPEDEAELL ATIEHYSDRM
DALVGNLLDM SRLSAQMVRP VAGPVTWQEV LPGALHGVPS ERVRRELPPN MPPIEADPGL
LERVIANIVE NAVKYAPDSD ILVVGSVGGS GSATINGRPA SELRVIDHGR GVPAAEVMAM
FRPFQRLDDV SYGPHGGSGV GLGLAVAKGF TEIMGGVLEA EQTPGGGLTM TIRMPLSTGI
VRTLP
//
