ID A0A0A1DFF4_NOCSI Unreviewed; 724 AA.
AC A0A0A1DFF4;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:GEB12419.1};
DE SubName: Full=Transmembrane transport protein MmpL13 {ECO:0000313|EMBL:AIY15971.1};
GN ORFNames=KR76_02915 {ECO:0000313|EMBL:AIY15971.1}, NSI01_07340
GN {ECO:0000313|EMBL:GEB12419.1};
OS Nocardioides simplex (Arthrobacter simplex).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Pimelobacter.
OX NCBI_TaxID=2045 {ECO:0000313|EMBL:AIY15971.1, ECO:0000313|Proteomes:UP000030300};
RN [1] {ECO:0000313|EMBL:AIY15971.1, ECO:0000313|Proteomes:UP000030300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-2033D {ECO:0000313|EMBL:AIY15971.1,
RC ECO:0000313|Proteomes:UP000030300};
RX PubMed=25573942;
RA Shtratnikova V.Y., Schelkunov M.I., Pekov Y.A., Fokina V.V.,
RA Logacheva M.D., Sokolov S.L., Bragin E.Y., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Steroid-Transforming Nocardioides simplex VKM
RT Ac-2033D.";
RL Genome Announc. 3:0-0(2015).
RN [2] {ECO:0000313|EMBL:GEB12419.1, ECO:0000313|Proteomes:UP000318936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 12069 {ECO:0000313|EMBL:GEB12419.1,
RC ECO:0000313|Proteomes:UP000318936};
RA Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT "Whole genome shotgun sequence of Pimelobacter simplex NBRC 12069.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP009896; AIY15971.1; -; Genomic_DNA.
DR EMBL; BJMC01000005; GEB12419.1; -; Genomic_DNA.
DR RefSeq; WP_038676499.1; NZ_JAAARG010000193.1.
DR AlphaFoldDB; A0A0A1DFF4; -.
DR STRING; 2045.KR76_02915; -.
DR KEGG; psim:KR76_02915; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_5_1_11; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000030300; Chromosome.
DR Proteomes; UP000318936; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030300};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 580..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..649
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 205..329
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 703..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 76442 MW; FE7871851602B946 CRC64;
MIERWGALVV RRAVAVLLVG LGVTALAALA GVGLEDKLAA GGFDDPGTES ARELVQERAA
FGNRSIDTIV LFSSDDATVS DTAFRAEVER TVASIPRDSV VSVATWYDAQ DPAMVSTDRH
ATAVYVSLAG SSQNEFIDSF DELRPAVEKS TLHTELAGPY AVYSDVNEET KSDLLRAELV
SLPVVLLLSL IIFRSVVAAL MPLLVGAVAV LGARATIAGL NQVVDVSIFA PNIITLLGLG
LAIDYALFVV SRFREEIART PDDTRRALVR TMATAGRTVA FSALTVAAAM SSLLVFPQTF
LKSIGYGGIA AVLIAMVAAL TVLPATLALL GTRIDALRIP FLQRSTPVES DHGAWARLAR
GVMRRPIVVA TAVAVVLLAV ASPFLGVKWG SVDYRVLPAD TASHQASERL NSEFGPERST
ANILVRDADE AALASYTRGL EGVPGVVDVR AVASDDGATL LRAAWEGNSQ TEASQQVVRD
LRAVPAPPGS EALVGGLTAD TVDLAASVGD HLPLMGLIVV GVMLVLLFLA FGSVVLPLKA
VLMNAFSITA SFGVVTWIFS DGHLSGLLGF TPQGFLDMTN PIVMLAVLFG LSMDYEVFLL
SRVREQWDAT GDNDLAVQTG VQKTGRIITS AALLLAVVIG AFSLSGVVFM KMMGLGMLVA
ILVDATVVRA LLVPATMKLL GRWNWWAPAP LARWWARHGF REGGPDDDAG SAPTDERQPV
PAGA
//
