ID A0A0A1DKK7_NOCSI Unreviewed; 445 AA.
AC A0A0A1DKK7;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Crotonyl-CoA carboxylase/reductase, ethylmalonyl-CoA producing {ECO:0000313|EMBL:AIY17088.1};
DE SubName: Full=Crotonyl-CoA reductase {ECO:0000313|EMBL:GEB13060.1};
GN ORFNames=KR76_10630 {ECO:0000313|EMBL:AIY17088.1}, NSI01_13750
GN {ECO:0000313|EMBL:GEB13060.1};
OS Nocardioides simplex (Arthrobacter simplex).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Pimelobacter.
OX NCBI_TaxID=2045 {ECO:0000313|EMBL:AIY17088.1, ECO:0000313|Proteomes:UP000030300};
RN [1] {ECO:0000313|EMBL:AIY17088.1, ECO:0000313|Proteomes:UP000030300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-2033D {ECO:0000313|EMBL:AIY17088.1,
RC ECO:0000313|Proteomes:UP000030300};
RX PubMed=25573942;
RA Shtratnikova V.Y., Schelkunov M.I., Pekov Y.A., Fokina V.V.,
RA Logacheva M.D., Sokolov S.L., Bragin E.Y., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Steroid-Transforming Nocardioides simplex VKM
RT Ac-2033D.";
RL Genome Announc. 3:0-0(2015).
RN [2] {ECO:0000313|EMBL:GEB13060.1, ECO:0000313|Proteomes:UP000318936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 12069 {ECO:0000313|EMBL:GEB13060.1,
RC ECO:0000313|Proteomes:UP000318936};
RA Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT "Whole genome shotgun sequence of Pimelobacter simplex NBRC 12069.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009896; AIY17088.1; -; Genomic_DNA.
DR EMBL; BJMC01000008; GEB13060.1; -; Genomic_DNA.
DR RefSeq; WP_038678152.1; NZ_JAAARG010000263.1.
DR AlphaFoldDB; A0A0A1DKK7; -.
DR STRING; 2045.KR76_10630; -.
DR KEGG; psim:KR76_10630; -.
DR eggNOG; COG0604; Bacteria.
DR HOGENOM; CLU_026673_5_0_11; -.
DR OrthoDB; 9790818at2; -.
DR Proteomes; UP000030300; Chromosome.
DR Proteomes; UP000318936; Unassembled WGS sequence.
DR GO; GO:0043880; F:crotonyl-CoA reductase activity; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR010085; Crot_CoA_red.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR NCBIfam; TIGR01751; crot-CoA-red; 1.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030300}.
FT DOMAIN 48..415
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 445 AA; 49131 MW; 69C3B980A79AF4CE CRC64;
MQHILDAIQA EASAEDFANL ELPESYRAVT VHKDEVDMFE GIDSRDKDPR KSLHVDEVAL
PELGPGEAFV AVMASAINYN TVWTSIFEPV STFGFLERYG RESDLGARHN LDYHIVGSDL
SGVVLAVGAG VTKWKPGDRV VAHCLSVELE APDGHNDTMM DPSQRIWGFE TNFGGLADVA
MVKANQLMPK PEHLTWEEAA SPGLVNCTAY RQLVSANGGN MKQGDNVLIW GASGGLGGFA
TQYALNGGAN PICVVSNEEK AQIVRNMGAE MVINRSELAP KFWNEEGTKQ NPKEWQRFGK
AIRELTGGED IDIVFEHPGR ETFGASVYVT RKGGTITTCA STSGYMHEYD NRYLWMNLKK
IISSHFANYR ESWEANRLIA QGKIHPTLSR TYKLEDTGQA ALDVHHNKHQ GKVGVLCLSP
EEGLGVRNGE MREQHLDKIN LFRGI
//
