ID A0A0A1DR63_NOCSI Unreviewed; 465 AA.
AC A0A0A1DR63;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Cytosine/purine/uracil/thiamine/allantoin permease family protein {ECO:0000313|EMBL:AIY17890.1};
GN ORFNames=KR76_15965 {ECO:0000313|EMBL:AIY17890.1};
OS Nocardioides simplex (Arthrobacter simplex).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Pimelobacter.
OX NCBI_TaxID=2045 {ECO:0000313|EMBL:AIY17890.1, ECO:0000313|Proteomes:UP000030300};
RN [1] {ECO:0000313|EMBL:AIY17890.1, ECO:0000313|Proteomes:UP000030300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-2033D {ECO:0000313|EMBL:AIY17890.1,
RC ECO:0000313|Proteomes:UP000030300};
RX PubMed=25573942;
RA Shtratnikova V.Y., Schelkunov M.I., Pekov Y.A., Fokina V.V.,
RA Logacheva M.D., Sokolov S.L., Bragin E.Y., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Steroid-Transforming Nocardioides simplex VKM
RT Ac-2033D.";
RL Genome Announc. 3:0-0(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
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DR EMBL; CP009896; AIY17890.1; -; Genomic_DNA.
DR RefSeq; WP_038679661.1; NZ_JAAARG010000343.1.
DR AlphaFoldDB; A0A0A1DR63; -.
DR STRING; 2045.KR76_15965; -.
DR KEGG; psim:KR76_15965; -.
DR eggNOG; COG1457; Bacteria.
DR HOGENOM; CLU_026016_3_0_11; -.
DR OrthoDB; 9809167at2; -.
DR Proteomes; UP000030300; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11484; SLC-NCS1sbd_CobB-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR PANTHER; PTHR31806; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR PANTHER; PTHR31806:SF1; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
DR PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW Reference proteome {ECO:0000313|Proteomes:UP000030300};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002744}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 465 AA; 48993 MW; 948C2451AEA4C8E8 CRC64;
MSADQSVVEK HTIGYVPPED RHGKVRDLFT LWFGTNIAPL PVVTGAAGVT VFGLDLFWCV
VAIVVGHLVG GIFMALHSAQ GPQMGIPQMI QSRGQFGSYG ALIVVVIAAV MYLAFFASNI
VLAGQSLHGI ADPVPVSTGI ILGALGSGLI CVIGYRFIHA LNKIATWVLG VGIVLAIGAI
FVSGLPGDFW SRGGYTTAGF LATVSLAALW QIAFAPYVSD YSRYLPAEVG VRATFNATYL
GCTLGSILPF AFGAVVALAM VPGTDVMTGV RDTTGSLGTP LLVLFLLSVI SHNALNLYGT
VLSMITCVQT FVARWIPTAR TRVVLSAVVM AAAAYFAIGV SGDFISHFVD IVLALLVVLV
PWTAINLIDF YLIHRGNYDL DSIFAADGGI YGRFNPQAIT AYVIGILVQI PFMNTPLYQG
PISDNLGGAD LSWIIGLVAT GPVYYLLARG RKLAPSELTG AVTAA
//
