ID   A0A0A1F5J3_9BURK        Unreviewed;       386 AA.
AC   A0A0A1F5J3;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE            EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN   ORFNames=LT85_0601 {ECO:0000313|EMBL:AIY39761.1};
OS   Collimonas arenae.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Collimonas.
OX   NCBI_TaxID=279058 {ECO:0000313|EMBL:AIY39761.1, ECO:0000313|Proteomes:UP000030302};
RN   [1] {ECO:0000313|EMBL:AIY39761.1, ECO:0000313|Proteomes:UP000030302}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Cal35 {ECO:0000313|EMBL:AIY39761.1,
RC   ECO:0000313|Proteomes:UP000030302};
RA   Uroz S., Tech J.J., Sawaya N.A., Frey-Klett P., Leveau J.H.J.;
RT   "Structure and function of bacterial communities in ageing soils: insights
RT   from the Mendocino ecological staircase.";
RL   Soil Biol. Biochem. 69:265-274(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC         methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC         ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR   EMBL; CP009962; AIY39761.1; -; Genomic_DNA.
DR   RefSeq; WP_038485077.1; NZ_CP009962.1.
DR   AlphaFoldDB; A0A0A1F5J3; -.
DR   STRING; 279058.LT85_0601; -.
DR   KEGG; care:LT85_0601; -.
DR   HOGENOM; CLU_009834_22_1_4; -.
DR   OrthoDB; 9790967at2; -.
DR   Proteomes; UP000030302; Chromosome.
DR   GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR   CDD; cd06558; crotonase-like; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR045004; ECH_dom.
DR   InterPro; IPR032259; HIBYL-CoA-H.
DR   PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR   Pfam; PF16113; ECH_2; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AIY39761.1}.
FT   DOMAIN          24..371
FT                   /note="Enoyl-CoA hydratase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF16113"
SQ   SEQUENCE   386 AA;  42366 MW;  D5E1A4E67B35DD96 CRC64;
     MEDVVKAAAP ALFEELIAEN GKRIGVATLN VEKTLNAISL EMVDLLDVQL RAWANDAGIA
     MVVLQAAGEK AFCAGGDLQD LYRTMLDQHA SGQREDITSN TYACDFFERE YRLDYLIHTY
     PKPMLAWAHG IVMGGGVGLM AGASHRVVTE KSRLAMPEIT IGLYPDVGGT WFLNRMPGQL
     GLFLALTGAS IGAADAIFAR LADYQIDHAQ KQALLETLLV QPWDGRQDDV LLTRVLLDAE
     HKAATTFAAA AMPLRQHFEL IHQLCSAPTL GEVVQNIVDL KTDDAWLQKG IVTLVAGSPA
     STWLSHDLQK RALHMSLAEV FRLEYVVSLH CAARADFAEG IRALIIDKDR QPKWQPATLA
     EVASDWGNGF FDNPWPEKNH PLADLS
//