ID   A0A0A1H7M1_9BURK        Unreviewed;      1164 AA.
AC   A0A0A1H7M1;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=E1O_20440 {ECO:0000313|EMBL:BAP89175.1};
OS   Burkholderiales bacterium GJ-E10.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX   NCBI_TaxID=1469502 {ECO:0000313|EMBL:BAP89175.1, ECO:0000313|Proteomes:UP000031649};
RN   [1] {ECO:0000313|EMBL:BAP89175.1, ECO:0000313|Proteomes:UP000031649}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GJ-E10 {ECO:0000313|EMBL:BAP89175.1,
RC   ECO:0000313|Proteomes:UP000031649};
RA   Fukushima J., Tojo F., Asano R., Kobayashi Y., Shimura Y., Okano K.,
RA   Miyata N.;
RT   "Complete Genome Sequence of the Unclassified Iron-Oxidizing,
RT   Chemolithoautotrophic Burkholderiales bacterium GJ-E10 Isolated from Acid
RT   River.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; AP014683; BAP89175.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A1H7M1; -.
DR   STRING; 1469502.E1O_20440; -.
DR   KEGG; bbag:E1O_20440; -.
DR   HOGENOM; CLU_001114_0_0_4; -.
DR   OrthoDB; 5905204at2; -.
DR   Proteomes; UP000031649; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF23; RECBCD ENZYME SUBUNIT RECB; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000031649}.
FT   DOMAIN          10..502
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          542..839
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
FT   REGION          546..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         31..38
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   1164 AA;  126315 MW;  4ECBAFD017A00906 CRC64;
     MSEYTVDGAA VPHERFIARA LDPARSCVVE ACAGSGKTWL LVGRILRALL AGAAPGQILA
     ITFTRRAAQE MRGRLLADLG TLACGTDDEA LAMLRLRGLS PDEAARVLPA ARGLYERVTV
     AENPIAIETF HGWFGRLLRA APIETGPGVY EQTLVDRIEP WMDEAWADFC ALLLRPDSAD
     RLRDYEELVR WTGDAAAETL LRNFVRHRAD WWCFRGSDSD DEAIARSSAP MRARLRELLG
     ADDRSPAAAL QAPQLRADLI AMCETWRAIP DPGVYLRNAI AGAEAWLAAQ DVRGGEASDA
     ACLAAFLDII LTQNGTPRTV LDPDRIEKKC KQVPEGPAAY RARHQSIVAA AEALRDAQME
     WEALRINECG LRCGAHLLAG FQERKRRAGA VDFTDLEWIA HQLLVDPDCA AYTQSWLDAR
     YRHLLVDEFQ DTNPLQWQIL QSWLAAYDGD ADRPSVFLVG DPKQSIYRFR GAEPRVFDVA
     RACLARDFGA AALRTNVTRR NAPELVALFN QVFSGANPLY QGQRTLASTS GGFAVLPRIA
     PQTGRGAGGA AGSAMEGAAG DGAARPRDAL TQARAEEIRD ERYREGLQLA AAIAAWRACT
     TVPEGAAERP ARWSDVLVLV RRRTYAGELE RAFRDAGIPF LSARRGSLLQ QLEVEDLIAL
     LEFLAAPDDD LQLARALRSP VFDCDEEDLR ALADTGEHPA PHAPGATSGA ELPDCWWSRL
     STRTAASPAL GRARDLLSRW LPLAGVLPVH DLLDRVIHES DLRARYAAAA PVTAGAQIQA
     NIDALLELAL TLDAGRFPSL ARFLGELRDL RDADDSNADE GIAADEDAVH LMTVHAAKGL
     EAPIVVLPDT HLPDAQEDRN DVLVAWLPDR PAPDHVSLIA RLSRMGTSRL PWIEQDRAQR
     RQEDWNLLYV AMTRAQQVLL VSGVDSPRAG SGTWYERIAA HAPPQAGAEP ELPRPVDRLP
     GAGADPRAAA AGPRFRDFRP ARVPVPALVP GPVGSRNAAE QTEAQRIGIA WHALLERAGG
     QETGTVSAER VAREFAISPS DAQAAIAAAE RVRNAPDLAQ FFTPAGTGPV IAADAELELV
     ARDGSLLRID RLVEFDDAIW ILDFKWSLNA ASLPGYRAQL QRYAQALADA GLGEGPEGAA
     QAQRKPIRML LVGSDGATAA VARD
//