ID A0A0A1MQ41_9BACI Unreviewed; 624 AA.
AC A0A0A1MQ41;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Sporulenol synthase {ECO:0000313|EMBL:CEI81737.1};
GN Name=sqhC {ECO:0000313|EMBL:CEI81737.1};
GN ORFNames=BN997_01582 {ECO:0000313|EMBL:CEI81737.1};
OS Oceanobacillus oncorhynchi.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX NCBI_TaxID=545501 {ECO:0000313|EMBL:CEI81737.1, ECO:0000313|Proteomes:UP000040453};
RN [1] {ECO:0000313|EMBL:CEI81737.1, ECO:0000313|Proteomes:UP000040453}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Oc5 {ECO:0000313|EMBL:CEI81737.1,
RC ECO:0000313|Proteomes:UP000040453};
RA Urmite Genomes Urmite Genomes;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Secondary metabolite biosynthesis; hopanoid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004999}.
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755}.
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DR EMBL; CDGG01000001; CEI81737.1; -; Genomic_DNA.
DR RefSeq; WP_042531082.1; NZ_CDGG01000001.1.
DR AlphaFoldDB; A0A0A1MQ41; -.
DR STRING; 545501.BN997_01582; -.
DR OrthoDB; 9758578at2; -.
DR UniPathway; UPA00337; -.
DR Proteomes; UP000040453; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR006400; Hopene-cyclase.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01507; hopene_cyclase; 1.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000040453};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 254..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..291
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 306..621
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 624 AA; 71531 MW; FAD3EFA9FF48FC73 CRC64;
MKEKIDVEIN RLVDRLTKEQ EHDGSWAYPF ETGISTDCYM IILLRTLEMD DEDLIDALVS
RILRKQGKNG AWKIFHDEVE GNLTATVEAC YALLYSGRRK EEDREIRLAT KFIQRHGGLK
EINMFAKVML ALTGQYKWPR YLPVPVKFIL FPVSFPLNLF DLSLYARSNL VPILITADYK
FSRKTKRSPD LSDLFLQRED DGDWETELND WRSFQTPFGR EISSLIGKPE QLHELALQRA
EEYMLNRRES DGTFYSYFSA TFLMIFALMA RGYSKKDPII IKAVEGLKAF QTSIGKQTHM
QYTTANVWNT ALISHALQKA GVSPSATVIK KANQYLLGRQ QMKYGDWSIH NQDVTPGGWG
FSHINTFNPD LDDTTAALRS IRSFARHTPV YRQAWDRGIQ WAVSMQNDDG GWPAFEKNVD
NTLLSWLPIE GGGSMLLDPS TADLTGRTLE FFGNDTHTDT YQPFIKRGMK WLLQNQEKDG
SWYGRWGICY IYGTWSAITG LAAVKTRSNH PQMQKAIQWL YAIQNQDGGW GESCKSDIEK
KYVPLKESTR THTAWALDAL IAAEGKATPE IKRGIAYLLE TAEKVDWTTA YPKGQGLPGG
FYIHYHSYEY LFPLLALANY REKF
//
