ID A0A0A1TMH7_9HYPO Unreviewed; 396 AA.
AC A0A0A1TMH7;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=UPF0020 domain-containing protein {ECO:0000259|Pfam:PF01170};
GN ORFNames=VHEMI07859 {ECO:0000313|EMBL:CEJ92193.1};
OS [Torrubiella] hemipterigena.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae;
OC Clavicipitaceae incertae sedis; 'Torrubiella' clade.
OX NCBI_TaxID=1531966 {ECO:0000313|EMBL:CEJ92193.1, ECO:0000313|Proteomes:UP000039046};
RN [1] {ECO:0000313|EMBL:CEJ92193.1, ECO:0000313|Proteomes:UP000039046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Horn F., Habel A., Scharf D.H., Dworschak J., Brakhage A.A., Guthke R.,
RA Hertweck C., Linde J.;
RT "Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus
RT Verticillium hemipterigenum.";
RL Genome Announc. 3:e01439-e01414(2015).
CC -!- FUNCTION: Catalytic subunit of an S-adenosyl-L-methionine-dependent
CC tRNA methyltransferase complex that mediates the methylation of the
CC guanosine nucleotide at position 10 (m2G10) in tRNAs.
CC {ECO:0000256|ARBA:ARBA00002425}.
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DR EMBL; CDHN01000004; CEJ92193.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A1TMH7; -.
DR STRING; 1531966.A0A0A1TMH7; -.
DR HOGENOM; CLU_029646_3_0_1; -.
DR OrthoDB; 5488599at2759; -.
DR Proteomes; UP000039046; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016691; tRNA_mtfrase_TRM11.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF3; TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PIRSF; PIRSF017259; tRNA_mtfrase_TRM11; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51627; SAM_MT_TRM11; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000039046};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 181..295
FT /note="UPF0020"
FT /evidence="ECO:0000259|Pfam:PF01170"
SQ SEQUENCE 396 AA; 44385 MW; 847F76FE003A5834 CRC64;
MEFIIKFAQA HETFRVAEIQ ALAEVEAVNL EIVHYENDSP LCIVRLESPE HAARLVRRSI
LAQSIHQLYG SGDTLAQLHD NLRNLDSSVW KQYEQSSFKF VIDSYQGSRP NAKRLELINS
FSYLPLKGKI QMSKPDEIFT VFDIWPFDSV PMGIENPTKI FLGRYIANSS RDVVLKFDLK
KRHYISTTSM DSELALITAN IALAAPGKIF YDPFVGTGSF PVACAHFGAM AWGSDIDGRS
IRGEGDGKCL VSNFEQYSLL GRLGDAFAAD ITNSPIQPGR RIWDGIVCDP PYGVREGLRV
LGVRDPEKTP WVIEKGIQLA SSPDFIPPKK PYSFFAILDD ILEFAAQTLV DGGRLSFWMP
TANEEDQQIP PPTHPRLETI SICIQSFNRC KYISNS
//
